P2X7 antagonists improve "in vitro" myelination in organotypic dorsal root ganglia (DRG) cultures from a rat model of CMT1A neuropathy

被引：0
|
作者：
Nobbio, L. [1 ,2 ]
Mannino, E. [2 ,3 ]
Visigalli, D. [1 ,2 ]
Fiorese, F. [1 ,2 ]
Basile, G. [2 ,3 ]
Sturla, L. [2 ,3 ]
Kassack, M. U. [4 ]
De Flora, A. [2 ,3 ]
Zocchi, E. [2 ,3 ]
Schenone, A. [1 ,2 ]
Bruzzone, S. [2 ,3 ]
机构：
[1] Univ Genoa, Dept Neurosci Ophthalmol & Genet, Genoa, Italy
[2] Univ Genoa, CEBR, Genoa, Italy
[3] Univ Genoa, Dept Expt Med, Biochem Sect, Genoa, Italy
[4] Univ Dusseldorf, Inst Pharmaceut & Med Chem, Dusseldorf, Germany
来源：
FEBS JOURNAL | 2011年 / 278卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：267 / 268
页数：2
相关论文
共 50 条
  • [21] A P2X7 antagonist improves muscle strength and motor distal amplitude in CMT1A rats: preliminary results from an in vivo trial
    Sociali, Giovanna
    Prukop, Thomas
    Cervellini, Ilaria
    Nobbio, Lucilla
    Bruzzone, Santina
    Schenone, Angelo
    Sereda, Michael W.
    PURINERGIC SIGNALLING, 2014, 10 (04) : 843 - 844
  • [22] P2X7-mediated Increased Intracellular Calcium Causes Functional Derangement in Schwann Cells from Rats with CMT1A Neuropathy
    Nobbio, Lucilla
    Sturla, Laura
    Fiorese, Fulvia
    Usai, Cesare
    Basile, Giovanna
    Moreschi, Iliana
    Benvenuto, Federica
    Zocchi, Elena
    De Flora, Antonio
    Schenone, Angelo
    Bruzzone, Santina
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (34) : 23146 - 23158
  • [23] The P2X7 Receptor Is Involved in Diabetic Neuropathic Pain Hypersensitivity Mediated by TRPV1 in the Rat Dorsal Root Ganglion
    Wang, Anhui
    Shi, Xiangchao
    Yu, Ruoyang
    Qiao, Bao
    Yang, Runan
    Xu, Changshui
    FRONTIERS IN MOLECULAR NEUROSCIENCE, 2021, 14
  • [24] Discovery and Biological Evaluation of Novel Cyanoguanidine P2X7 Antagonists with Analgesic Activity in a Rat Model of Neuropathic Pain
    Perez-Medrano, Arturo
    Donnelly-Roberts, Diana L.
    Honore, Prisca
    Hsieh, Gin C.
    Namovic, Marian T.
    Peddi, Sridhar
    Shuai, Qi
    Wang, Ying
    Faltynek, Connie R.
    Jarvis, Michael F.
    Carroll, William A.
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (10) : 3366 - 3376
  • [25] LncRNA NONRATT021972 siRNA regulates neuropathic pain behaviors in type 2 diabetic rats through the P2X7 receptor in dorsal root ganglia
    Shuangmei Liu
    Lifang Zou
    Jinyan Xie
    Wei Xie
    Shiyao Wen
    Qiuyu Xie
    Yun Gao
    Guilin Li
    Chunping Zhang
    Changshui Xu
    Hong Xu
    Bing Wu
    Qiulan Lv
    Xi Zhang
    Shouyu Wang
    Yun Xue
    Shangdong Liang
    Molecular Brain, 9
  • [26] LncRNA NONRATT021972 siRNA regulates neuropathic pain behaviors in type 2 diabetic rats through the P2X7 receptor in dorsal root ganglia
    Liu, Shuangmei
    Zou, Lifang
    Xie, Jinyan
    Xie, Wei
    Wen, Shiyao
    Xie, Qiuyu
    Gao, Yun
    Li, Guilin
    Zhang, Chunping
    Xu, Changshui
    Xu, Hong
    Wu, Bing
    Lv, Qiulan
    Zhang, Xi
    Wang, Shouyu
    Xue, Yun
    Liang, Shangdong
    MOLECULAR BRAIN, 2016, 9
  • [27] Electroacupuncture alleviates neuropathic pain in a rat model of CCD via suppressing P2X3 expression in dorsal root ganglia
    Zheng, Yu
    Jiang, Minjian
    Wei, Zhouyuan
    Chi, Hengyu
    Kang, Yurong
    Li, Siyi
    Zheng, Yinmu
    He, Xiaofen
    Shao, Xiaomei
    Fang, Jianqiao
    Jiang, Yongliang
    CHINESE MEDICINE, 2024, 19 (01):
  • [28] Effect of GLT-1 modulator and P2X7 antagonists alone and in combination in the kindling model of epilepsy in rats
    Soni, Neha
    Koushal, Prashant
    Reddy, B. V. K.
    Deshmukh, Rahul
    Kumar, Puneet
    EPILEPSY & BEHAVIOR, 2015, 48 : 4 - 14
  • [29] Catestatin Enhances Neuropathic Pain Mediated by P2X4 Receptor of Dorsal Root Ganglia in a Rat Model of Chronic Constriction Injury
    Deng, Zeyu
    Li, Congcong
    Du, Errong
    Liu, Chenglong
    Xia, Bihan
    Chen, Huiyu
    He, Qiqing
    Xu, Changshui
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 51 (02) : 812 - 826
  • [30] Pharmacological blockade of the P2X7 receptor reverses retinal damage in a rat model of type 1 diabetes
    Clapp, Carmen
    Diaz-Lezama, Nundehui
    Adan-Castro, Elva
    Ramirez-Hernandez, Gabriela
    Moreno-Carranza, Bibiana
    Sarti, Alba Clara
    Falzoni, Simonetta
    Solini, Anna
    Di Virgilio, Francesco
    ACTA DIABETOLOGICA, 2019, 56 (09) : 1031 - 1036
12345