Prevention of mitochondrial diseases: a hope through assisted reproductive technologies

被引：0
|
作者：
Eduardo Pina-Aguilar, Raul [1 ]
机构：
[1] Univ Autonoma Yucatan, Fac Med, Adm Pens, Merida 97212, Yuc, Venezuela
来源：
GACETA MEDICA DE MEXICO | 2011年 / 147卷 / 02期
关键词：
Mitochondrial disease; mtDNA; Nuclear transfer; Chromosome transfer; Pronuclear transfer; DNA;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Mitochondrial diseases are a heterogenic and poorly studied group of diseases, considered serious in most cases and currently without treatment. Although assisted reproduction proposed strategies to prevent them, such as pre-implantation genetic diagnosis, these techniques are not sufficiently successful. However, the recent publication of two assisted-reproduction techniques - meiotic spindle transfer in nonhuman primates and pronuclear transfer in humans - generate a clear ray of hope for the prevention of these diseases. This review analyzes the characteristics and meaning of these new findings and their future clinical implications.
引用
收藏
页码：172 / 175
页数：4
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