Salivary IL-6 and IL-10 levels in subjects with obesity and gingivitis

被引：1
|
作者：
Dogan, Gulnihal Emrem [1 ]
Toraman, Ayse [1 ]
Sebin, Saime Ozbek [2 ]
Dogan, Cetin [3 ]
Gungor, Adem [3 ]
Aksoy, Hulya [4 ]
Asutay, Hilal [5 ]
机构：
[1] Ataturk Univ, Fac Dent, Dept Periodontol, TR-25240 Erzurum, Turkey
[2] Ataturk Univ, Fac Med, Dept Physiol, Erzurum, Turkey
[3] Ataturk Univ, Fac Med, Dept Internal Med, Erzurum, Turkey
[4] Ataturk Univ, Fac Med, Dept Med Biochem, Erzurum, Turkey
[5] Afyon Kocatepe Univ, Fac Dent, Dept Prosthodont, Afyon, Turkey
来源：
AMERICAN JOURNAL OF DENTISTRY | 2016年 / 29卷 / 05期
关键词：
NECROSIS-FACTOR-ALPHA; PERIODONTAL-DISEASE; CREVICULAR FLUID; CYTOKINE LEVELS; INTERLEUKIN-10; INFLAMMATION; OVERWEIGHT; ASSOCIATION; HEALTH;
D O I：
暂无
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Purpose: To evaluate the association between cytokines IL-6 and IL-10 in saliva, obesity and periodontal disease. Methods: The study was carried out in 40 subjects: 20 obese subjects with gingivitis and 20 non-obese subjects with gingivitis (controls). Periodontal parameters such as gingival index (GI) and plaque index (PI) of subjects were recorded. Saliva samples were used for measuring IL-6 and IL-10 levels by ELISA method. Results: Saliva IL-6 levels were significantly higher in obese subjects than those of non-obese subjects (P= 0.002). When total groups were evaluated, negative significant correlation between GI and salivary IL-10 levels (r= -0.452, P= 0.003) and positive correlations between salivary IL-6 level and body mass index (BMI) (r= 0.369, P= 0.019) were found. There was a negative correlation between the GI and salivary IL-10 levels in obese subjects (r= -0.548, P= 0.012). Also there was a positive correlation between the salivary level of IL-6 and IL-10 in obese subjects
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页码：261 / 265
页数：5
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