Integrons and gene cassettes in the Enterobacteriaceae

被引:392
|
作者
White, PA [1 ]
McIver, CJ
Rawlinson, WD
机构
[1] Prince Wales Hosp, Dept Microbiol, Div Virol, SEALS, Randwick, NSW 2031, Australia
[2] Univ New S Wales, Fac Med, Sch Pathol, Sydney, NSW 2052, Australia
[3] Univ New S Wales, Fac Sci, Sch Microbiol & Immunol, Sydney, NSW 2052, Australia
关键词
D O I
10.1128/AAC.45.9.2658-2661.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Integrons were detected in 59 of 120 (49%) urinary isolates of Enterobacteriaceae by PCR using degenerate primers targeted to conserved regions of class 1, 2, and 3 integrase genes. PCR sequencing analysis of the cassette arrays revealed a predominance of cassettes that confer resistance to the aminoglycosides and trimethoprim.
引用
收藏
页码:2658 / 2661
页数:4
相关论文
共 50 条
  • [21] Antibiotic resistance in gram-negative bacteria: the role of gene cassettes and integrons
    Hall, RM
    Collis, CM
    DRUG RESISTANCE UPDATES, 1998, 1 (02) : 109 - 119
  • [22] Detection of gene cassettes in Tn402-like class 1 integrons
    Post, Virginia
    Reechia, Gavin D.
    Hall, Ruth M.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (09) : 3467 - 3468
  • [23] GENE CASSETTES FROM THE INSERT REGION OF INTEGRONS ARE EXCISED AS COVALENTLY CLOSED CIRCLES
    COLLIS, CM
    HALL, RM
    MOLECULAR MICROBIOLOGY, 1992, 6 (19) : 2875 - 2885
  • [24] Sewage treatment plant serves as a hot-spot reservoir of integrons and gene cassettes
    Ma, Liping
    Zhang, Xu-Xiang
    Zhao, Fuzheng
    Wu, Bing
    Cheng, Shupei
    Yang, Liuyan
    JOURNAL OF ENVIRONMENTAL BIOLOGY, 2013, 34 (02): : 391 - 399
  • [25] Methods for the targeted sequencing and analysis of integrons and their gene cassettes from complex microbial communities
    Ghaly, Timothy M.
    Penesyan, Anahit
    Pritchard, Alexander
    Qi, Qin
    Rajabal, Vaheesan
    Tetu, Sasha G.
    Gillings, Michael R.
    MICROBIAL GENOMICS, 2022, 8 (03):
  • [26] MOBILE GENE CASSETTES AND INTEGRONS - CAPTURE AND SPREAD OF GENES BY SITE-SPECIFIC RECOMBINATION
    HALL, RM
    COLLIS, CM
    MOLECULAR MICROBIOLOGY, 1995, 15 (04) : 593 - 600
  • [27] Characterization and quantification of class 1 integrons and associated gene cassettes in sewage treatment plants
    Xu-Xiang Zhang
    Tong Zhang
    Ming Zhang
    Herbert H. P. Fang
    Shu-Pei Cheng
    Applied Microbiology and Biotechnology, 2009, 82 : 1169 - 1177
  • [28] A simple algorithm for identifying integrons and gene cassettes in bacteria on next generation sequencing data
    Hua, Guan-Jie
    Hung, Che-Lun
    Tang, Chuan Yi
    Zheng, Huiru
    INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 2016, 14 (01) : 40 - 50
  • [29] Context-driven discovery of gene cassettes in mobile integrons using a computational grammar
    Tsafnat, Guy
    Coiera, Enrico
    Partridge, Sally R.
    Schaeffer, Jaron
    Iredell, Jon R.
    BMC BIOINFORMATICS, 2009, 10 : 281
  • [30] Discovery and characterization of gene cassettes-containing integrons in clinical strains of Riemerella anatipestifer
    Zheng, Fuying
    Lin, Guozhen
    Zhou, Jizhang
    Cao, Xiaoan
    Gong, Xiaowei
    Wang, Guanghua
    Qiu, Changqing
    VETERINARY MICROBIOLOGY, 2012, 156 (3-4) : 434 - 438