Application of Reactive Oxygen Species in Dental Treatment

被引：8
|
作者：
Komine, Chiaki [1 ]
Uchibori, Satoshi [2 ]
Tsudukibashi, Osamu [1 ]
Tsujimoto, Yasuhisa [3 ]
机构：
[1] Nihon Univ, Sch Dent Matsudo, Dept Lab Med & Dent Compromised Patient, Chiba 2718587, Japan
[2] Nihon Univ, Sch Dent Matsudo, Dept Oral Funct & Fixed Prothodont, Chiba 2718587, Japan
[3] Nihon Univ, Sch Dent Matsudo, Dept Endodont, Chiba 2718587, Japan
来源：
JOURNAL OF PERSONALIZED MEDICINE | 2022年 / 12卷 / 09期
关键词：
reactive oxygen species; photolysis; antimicrobial photodynamic therapy; sterilization; smear layer removal; endodontic therapy; HYDROGEN-PEROXIDE PHOTOLYSIS; INDUCED OXIDATIVE STRESS; PHOTODYNAMIC THERAPY; MITOCHONDRIAL DYSFUNCTION; APICAL PERIODONTITIS; DISINFECTION SYSTEM; H2O2; CHEMISTRY; PHOTOSENSITIZERS; INACTIVATION;
D O I：
10.3390/jpm12091531
中图分类号：
R19 [保健组织与事业（卫生事业管理）];
学科分类号：
摘要：
Reactive oxygen species (ROS) and free radicals, which have been implicated in inflammation, pain, carcinogenesis, and aging, are actually used in dental treatments such as tooth bleaching and composite resin polymerization. Recently, numerous studies have investigated the application of ROS in the medical and dental fields. In previous studies, ROS were generated intentionally through pathways such as photolysis, photocatalytic methods, and photodynamic therapy, which are used in the medical field to target cancer. In the field of dentistry, generated ROS are applied mainly for periodontal treatment and sterilization of the root canal, and its effectiveness as an antibacterial photodynamic therapy has been widely reported.. Given this background, the present article aimed to review the basic effects of ROS in dental medicine, especially endodontic therapy, and to discuss future applications of ROS.
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页数：14
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