Zn (II)/spiroQuinox catalyzed asymmetric Friedel-Crafts alkylation of indoles with cyclic N-sulfonyl ketimino esters

被引：5
|
作者：
Li, Yanshun [1 ]
Dong, Mengqi [1 ]
Gao, Nanxing [1 ]
Cao, Guorui [1 ]
Teng, Dawei [1 ]
机构：
[1] Qingdao Univ Sci & Technol, Coll Chem Engn, Qingdao 266042, Peoples R China
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 2022年 / 36卷 / 05期
关键词：
asymmetric Friedel-Crafts alkylation; cyclic N-sulfonyl ketimino esters; indoles; spiroQuinox ligand; 3-SUBSTITUTED INDOLES; SIMPLE ENONES; ALDIMINES;
D O I：
10.1002/aoc.6635
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Zinc complex of a new spiroQuinox ligand with a spirocarbon stereogenic center was examined for asymmetric Friedel-Crafts alkylation of indoles with cyclic N-sulfonyl ketimino esters. This catalytic system provides a platform for facile synthesis of benzosultam derivatives functionalized with indole substituents, in high yield and excellent enantioselectivity.
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页数：8
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