Conservative hypothesis tests and confidence intervals using importance sampling

被引:14
|
作者
Harrison, Matthew T. [1 ]
机构
[1] Brown Univ, Div Appl Math, Providence, RI 02912 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
Exact inference; Monte Carlo simulation; Multiple testing; p-value; Rasch model; LOGISTIC-REGRESSION; INFERENCE;
D O I
10.1093/biomet/asr079
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Importance sampling is a common technique for Monte Carlo approximation, including that of p-values. Here it is shown that a simple correction of the usual importance sampling p-values provides valid p-values, meaning that a hypothesis test created by rejecting the null hypothesis when the p-value is at most alpha will also have a Type I error rate of at most alpha. This correction uses the importance weight of the original observation, which gives valuable diagnostic information under the null hypothesis. Using the corrected p-values can be crucial for multiple testing and also in problems where evaluating the accuracy of importance sampling approximations is difficult. Inverting the corrected p-values provides a useful way to create Monte Carlo confidence intervals that maintain the nominal significance level and use only a single Monte Carlo sample.
引用
收藏
页码:57 / 69
页数:13
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