Fat-predominant mixed epithelial stromal tumor (MEST): Report of a unique case mimicking angiomyolipoma

被引：4

作者：

Sireci, Anthony N. ^{[1
]}

Rodriguez, Ronald ^{[2
,3
]}

Swierczynski, Sharon L. ^{[4
,5
]}

Netto, George J. ^{[1
,2
]}

Argani, Pedram ^{[1
,3
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA

[2] Johns Hopkins Univ, Sch Med, Dept Urol, Baltimore, MD 21205 USA

[3] Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA

[4] Reading Hosp, Dept Pathol, Reading, PA USA

[5] Med Ctr, Reading, PA USA

来源：

INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY | 2008年 / 16卷 / 01期

关键词：

mixed epithelial stromal tumor; kidney; angiomyolipoma; fat;

D O I：

10.1177/1066896907304523

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

A unique case of a mixed epithelial stromal tumor (MEST) that was predominantly composed of adipose tissue is reported here. Radiographically and grossly, the lesion was thought to be an angiomyolipoma, based upon its fatty appearance. Microscopically, the lesion was predominantly composed of mature adipose tissue but also contained clusters of bland tubules surrounded by smooth muscle bundles and collagen. By immunohistochemistry, the stroma labeled diffusely for estrogen and progesterone receptors, while the muscle bundles labeled for desmin. Melanocytic markers HMB45 and Melan A, typically positive in angiomyolipoma, were nonreactive. This case expands the morphologic spectrum of MEST to include mimics of angiomyolipoma.

引用

页码：73 / 77

页数：5

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