sentinel lymph node biopsy;
tomography;
emission-computed;
single-photon;
head and neck neoplasms;
melanoma;
radionuclide imaging;
BIOPSY;
LYMPHOSCINTIGRAPHY;
CT;
IDENTIFICATION;
CANCER;
D O I:
10.1002/hed.21392
中图分类号:
R76 [耳鼻咽喉科学];
学科分类号:
100213 ;
摘要:
Background. The additional value of single photon emission computed tomography with CT (SPECT/CT) for detection and localization of sentinel nodes in patients with a melanoma of the head and neck was determined, Methods. Thirty-eight patients received conventional lymphoscintigraphy followed by hybrid SPECT/CT. The number of sentinel nodes visualized and anatomic information provided were analyzed. Changes in surgical approach due to additional information from the SPECT/CT were evaluated in 20 patients. Results. SPECT/CT visualized a mean of 2.6 sentinel nodes per patient (range, 1-6). SPECT/CT depicted an additional sentinel node in 16% of the patients and clearly showed the anatomic location of the hot nodes in all patients. The surgical approach was adjusted on the basis of SPECT/CT images in 11 patients (55%). Conclusion. SPECT/CT visualizes more sentinel nodes than conventional images and shows their anatomic location. SPECT/CT is recommended in patients with a melanoma in the head or neck. (C) 2010 Wiley Periodicals, Inc. Head Neck 33: 1-6, 2011
机构:
Calif Pacific Med Ctr & Res Inst, Ctr Melanoma Res & Treatment, San Francisco, CA 94115 USA
Calif Pacific Med Ctr & Res Inst, Dept Surg, San Francisco, CA 94115 USACalif Pacific Med Ctr & Res Inst, Ctr Melanoma Res & Treatment, San Francisco, CA 94115 USA