CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets

被引：54

作者：

Schofield, E. C. ^{[1
]}

Carver, T. ^{[1
]}

Achuthan, P. ^{[1
]}

Freire-Pritchett, P. ^{[2
]}

Spivakov, M. ^{[2
]}

Todd, J. A. ^{[1
]}

Burren, O. S. ^{[1
]}

机构：

[1] Univ Cambridge, JDRF Wellcome Trust Diabet & Inflammat Lab, NIHR Cambridge Biomed Res Ctr, Dept Med Genet,Cambridge Inst Med Res, Cambridge CB2 0XY, England

[2] Babraham Inst, Nucl Dynam Programme, Cambridge CB22 3AT, England

来源：

BIOINFORMATICS | 2016年 / 32卷 / 16期

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会;

关键词：

GENOME; CIRCOS;

D O I：

10.1093/bioinformatics/btw173

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Promoter capture Hi-C (PCHi-C) allows the genome-wide interrogation of physical interactions between distal DNA regulatory elements and gene promoters in multiple tissue contexts. Visual integration of the resultant chromosome interaction maps with other sources of genomic annotations can provide insight into underlying regulatory mechanisms. We have developed Capture HiC Plotter (CHiCP), a web-based tool that allows interactive exploration of PCHi-C interaction maps and integration with both public and user-defined genomic datasets.

引用

页码：2511 / 2513

页数：3

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