Hepatitis B virus infection in blood donors in Argentina: prevalence of infection, genotype distribution and frequency of occult HBV infection

被引：9

作者：

Belen Pisano, Maria ^{[1
]}

Blanco, Sebastian ^{[2
]}

Carrizo, Horacio ^{[2
]}

Elizabeth Re, Viviana ^{[1
]}

Gallego, Sandra ^{[1
,2
]}

机构：

[1] Univ Nacl Cordoba, Fac Ciencias Med, Inst Virol Dr JM Vanella, Enfermera Gordillo Gomez S-N,Ciudad Univ, RA-5016 Cordoba, Argentina

[2] Fdn Banco Cent Sangre, Cordoba, Argentina

来源：

ARCHIVES OF VIROLOGY | 2016年 / 161卷 / 10期

关键词：

HBV; Blood bank; Genotype; Prevalence; NAT; HUMAN-IMMUNODEFICIENCY-VIRUS; C VIRUS; PHYLOGENETIC ANALYSIS; GENETIC DIVERSITY; VIRAL-HEPATITIS; RESIDUAL RISK; UNITED-STATES; EPIDEMIOLOGY; HBSAG;

D O I：

10.1007/s00705-016-2960-2

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This study describes the prevalence of HBV infection based on detection of HBsAg and HBV-DNA by NAT in 70,102 blood donors in Argentina (Crdoba province) and shows the viral genotype distribution and frequency of occult HBV infection (OBI) in this population. Forty-two donors were confirmed positive for HBV infection (0.06 %), and four had OBI. Genotype F was the most prevalent (71.4 %), followed by A (14.3 %), C (7.1 %) and D (7.1 %). This is the first report of the prevalence of confirmed HBV infection and the high frequency of occult HBV infection in a blood bank in Argentina.

引用

页码：2813 / 2817

页数：5

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