Hepatitis B virus infection in blood donors in Argentina: prevalence of infection, genotype distribution and frequency of occult HBV infection

被引：9
|
作者：
Belen Pisano, Maria [1 ]
Blanco, Sebastian [2 ]
Carrizo, Horacio [2 ]
Elizabeth Re, Viviana [1 ]
Gallego, Sandra [1 ,2 ]
机构：
[1] Univ Nacl Cordoba, Fac Ciencias Med, Inst Virol Dr JM Vanella, Enfermera Gordillo Gomez S-N,Ciudad Univ, RA-5016 Cordoba, Argentina
[2] Fdn Banco Cent Sangre, Cordoba, Argentina
来源：
ARCHIVES OF VIROLOGY | 2016年 / 161卷 / 10期
关键词：
HBV; Blood bank; Genotype; Prevalence; NAT; HUMAN-IMMUNODEFICIENCY-VIRUS; C VIRUS; PHYLOGENETIC ANALYSIS; GENETIC DIVERSITY; VIRAL-HEPATITIS; RESIDUAL RISK; UNITED-STATES; EPIDEMIOLOGY; HBSAG;
D O I：
10.1007/s00705-016-2960-2
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
This study describes the prevalence of HBV infection based on detection of HBsAg and HBV-DNA by NAT in 70,102 blood donors in Argentina (Crdoba province) and shows the viral genotype distribution and frequency of occult HBV infection (OBI) in this population. Forty-two donors were confirmed positive for HBV infection (0.06 %), and four had OBI. Genotype F was the most prevalent (71.4 %), followed by A (14.3 %), C (7.1 %) and D (7.1 %). This is the first report of the prevalence of confirmed HBV infection and the high frequency of occult HBV infection in a blood bank in Argentina.
引用
收藏
页码：2813 / 2817
页数：5
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