Cutaneous hyperpigmentation following bleomycin sclerotherapy for vascular malformations

被引：5
|
作者：
Davis, Kyle P. [1 ]
Gaffey, Megan M. [1 ,2 ,3 ]
Kompelli, Anvesh R. [1 ]
Richter, Gresham T. [1 ,2 ]
机构：
[1] Univ Arkansas Med Sci, Dept Otolaryngol Head & Neck Surg, Little Rock, AR 72205 USA
[2] Arkansas Childrens Hosp, Div Pediat Otolaryngol, 800 Marshall St, Little Rock, AR 72202 USA
[3] NYU, Langone Hlth, Div Pediat Otolaryngol, Dept Otolaryngol Head & Neck Surg, New York, NY USA
来源：
PEDIATRIC DERMATOLOGY | 2022年 / 39卷 / 01期
关键词：
bleomycin; hyperpigmentation; sclerotherapy; vascular malformations; ANESTHESIA;
D O I：
10.1111/pde.14869
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Systemic bleomycin therapy is associated with pulmonary fibrosis and cutaneous side effects. While it is believed that there is little to no systemic distribution of bleomycin when utilized to treat vascular malformations (VMs), we present a case series in which cutaneous, adhesive-related hyperpigmentation suggests that there is systemic egress of bleomycin following direct puncture sclerotherapy (DPS). This risk of hyperpigmentation after intralesional bleomycin should be discussed with patients, and steps to minimize the chances of it occurring should be implemented.
引用
收藏
页码：103 / 106
页数：4
相关论文
共 50 条
  • [21] Patient-Reported Outcomes of Bleomycin Sclerotherapy for Low-Flow Vascular Malformations and Predictors of Improvement
    S. E. R. Horbach
    J. S. van de Ven
    P. T. Nieuwkerk
    Ph. I. Spuls
    C. M. A. M. van der Horst
    J. A. Reekers
    CardioVascular and Interventional Radiology, 2018, 41 : 1494 - 1504
  • [22] Short-term side effects and patient-reported outcomes of bleomycin sclerotherapy in vascular malformations
    Mack, Joana M.
    Richter, Gresham T.
    Becton, David
    Salem, Omar
    Hill, Sarah E. M.
    Crary, Shelley E.
    PEDIATRIC BLOOD & CANCER, 2018, 65 (06)
  • [23] Unexpected hyperpigmentation following intralesional bleomycin injection
    Sainsbury, D. C. G.
    Kessell, G.
    Guhan, A.
    Fall, A.
    Miller, V.
    Abouzeid, M. R.
    Muir, T.
    JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2009, 62 (11): : E497 - E499
  • [24] Simulated Angiography Using a Bleomycin Mixture for Sclerotherapy of Lymphatic Malformations
    Guo, Lei
    Wu, Changhua
    Li, Xiaoyan
    Song, Dan
    Sun, Jiali
    Zhang, Yunkui
    FRONTIERS IN PEDIATRICS, 2020, 8
  • [25] Single center experience with intralesional bleomycin sclerotherapy for lymphatic malformations
    Hakan Yılmaz
    Özlem Yılmaz
    İlkay Çamlıdağ
    Ümit Belet
    Hüseyin Akan
    Japanese Journal of Radiology, 2017, 35 : 590 - 596
  • [26] Single center experience with intralesional bleomycin sclerotherapy for lymphatic malformations
    Yilmaz, Hakan
    Yilmaz, Ozlem
    Camlidag, Ilkay
    Belet, Umit
    Akan, Huseyin
    JAPANESE JOURNAL OF RADIOLOGY, 2017, 35 (10) : 590 - 596
  • [27] OUTCOMES OF SCLEROTHERAPY FOR THE TREATMENT OF VENOUS VASCULAR MALFORMATIONS
    Gorman, J.
    Bucevska, M.
    Arneja, J.
    Courtemanche, D.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2014, 62 (01) : 185 - 185
  • [28] Foam sclerotherapy in various vascular and lymphatic malformations
    Ratnavel, G. R.
    INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2011, 77 (03): : 336 - U259
  • [29] Percutaneous Sclerotherapy for Vascular Malformations: A Systematic Review
    Gurgacz, Stefanie
    Zamora, Luis
    Scott, N. Ann
    ANNALS OF VASCULAR SURGERY, 2014, 28 (05) : 1335 - 1349
  • [30] Assessment of outcomes after intralesional bleomycin sclerotherapy of lymphatic malformations in children
    Mazhar, Aqsa
    Shazlee, Muhammad Kashif
    Abd Mallick, Yousuf
    Muhammad, Ammar Ali
    Samad, Lubna
    JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION, 2023, 73 (02) : 290 - 293
12345