β-alanine dipeptides as MC4R agonists

被引：23
|
作者：
Ruel, R
Herpin, TF
Iben, L
Luo, GL
Martel, A
Mason, H
Mattson, G
Poirier, B
Ruediger, EH
Shi, D
Thibault, C
Yu, GX
Zimanyi, IA
Poindexter, GS
Macor, JE
机构：
[1] Bristol Myers Squibb Co, Pharmaceut Res Inst, Candiac, PQ J5R 1J1, Canada
[2] Dept Metab Res, Princeton, NJ 08543 USA
[3] Dept Neurosci, Wallingford, CT 06492 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 24期
关键词：
D O I：
10.1016/j.bmcl.2003.09.036
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
beta-Alanine derivative 2 (IC50 = 16 nM) and related compounds were found to be potent MC4R agonists. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4341 / 4344
页数：4
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