Off-Label Use and Inappropriate Dosing of Direct Oral Anticoagulants in Cardiopulmonary Disease

被引：3

作者：

Hussein, Ayman A. ^{[1
]}

Alvarez, Paulino ^{[2
]}

Reed, Grant ^{[3
]}

Heresi, Gustavo A. ^{[4
]}

机构：

[1] Cleveland Clin, Dept Cardiovasc Med, Sect Cardiac Pacing & Electrophysiol, Cleveland, OH 44106 USA

[2] Cleveland Clin, Sect Heart Failure, Dept Cardiovasc Med, Cleveland, OH 44106 USA

[3] Cleveland Clin, Sect Intervent Cardiol, Dept Cardiovasc Med, Cleveland, OH 44106 USA

[4] Cleveland Clin, Dept Pulm & Crit Care Med, Cleveland, OH 44106 USA

来源：

CHEST | 2022年 / 161卷 / 05期

关键词：

direct oral anticoagulant; off-label use; thromboembolism; VALVULAR HEART-DISEASE; ATRIAL-FIBRILLATION; PULMONARY-HYPERTENSION; SINUS RHYTHM; ANTITHROMBOTIC THERAPY; VALVE THROMBOSIS; WARFARIN; FAILURE; OUTCOMES; STROKE;

D O I：

10.1016/j.chest.2022.01.033

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Direct oral anticoagulants (DOACs) are increasingly used in clinical practice and have become essential in the management of atrial fibrillation and VTE. The enthusiasm for DOACs has fueled the off-label application of these agents in cardiopulmonary disease, and their use has often outpaced the evidence supporting their application. This article reviews the evidence and current off-label use of DOACs in various cardiopulmonary disease states.

引用

页码：1360 / 1369

页数：10

共 50 条

[31] Off-label use of direct oral anticoagulants compared withwarfarin for left ventricular thrombi (vol 561, pg 81, 2020)
Robinson, A. A.
Trankle, C. R.
Eubanks, G.
[J]. JAMA CARDIOLOGY, 2020, 5 (06) : 732 - 732
[32] Predictors of inappropriate dosing of direct oral anticoagulants in nonagenarian patients with atrial fibrillation
Dominguez Erquicia, P.
Raposeiras-Roubin, S.
Abu-Asi, E.
Cespon-Fernandez, M.
Alonso Rodriguez, D.
Camacho Freire, S. J.
Curbelos Fernandez, N.
Masjuan Rios, A. Lopez
Melendo Viu, M.
Iniguez Romo, A.
[J]. EUROPEAN HEART JOURNAL, 2021, 42 : 2928 - 2928
[33] Off-label use of antipsychotics: Rethinking "off-label"
Groleger, Urban
[J]. PSYCHIATRIA DANUBINA, 2007, 19 (04) : 350 - 353
[34] Influence of off-label use of new oral anticoagulants in post-surgery: the risk of venous thromboembolism?
Gony, M.
Jacquot, J.
Bonenfant, S.
Rousseau, V.
Livry, C.
Pelagatti, V.
Montastruc, J. L.
Bagheri, H.
[J]. FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2013, 27 : 95 - 95
[35] Anticoagulants/prednisolone/remdesivirLack of efficacy and off-label use: case report
[J]. Reactions Weekly, 2023, 1943 (1) : 72 - 72
[36] Evaluation of off-label rapamycin use on oral health
Hudson, Johnny
Kaeberlein, Tammi
Mahal, Akashdeep
Wong, Nelson
Ghorbanifarajzadeh, Mina
Radella, Frank
Isman, Anar
Nyquist, Andy
Zalzala, Sajad
Haddad, George
Kaeberlein, Matt
An, Jonathan Y.
[J]. GEROSCIENCE, 2024, : 4135 - 4146
[37] Anticoagulants/antiplateletsBleeding events and off-label use: 26 case reports
[J]. Reactions Weekly, 2020, 1802 (1) : 42 - 42
[38] Current Antithrombotic Therapy Strategies in Children with a Focus on Off-Label Direct Oral Anticoagulants-A Narrative Review
Moisa, Stefana Maria
Trandafir, Laura Mihaela
Brinza, Crischentian
Miron, Ingrith Crenguta
Tarca, Elena
Butnariu, Lacramioara Ionela
Burlacu, Alexandru
[J]. CHILDREN-BASEL, 2022, 9 (07):
[39] Off-Label Under- and Overdosing of Direct Oral Anticoagulants in Patients With Atrial Fibrillation: A Meta-Analysis
Zhang, Xin-Lin
Zhang, Xiao-Wen
Wang, Ting-Yu
Wang, Hong-Wei
Chen, Zheng
Xu, Biao
Xu, Wei
[J]. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 2021, 14 (12): : 1224 - 1237
[40] Off-label dosing of non-vitamin K antagonist oral anticoagulants and clinical outcomes in Asian patients with atrial fibrillation
Chan, Yi-Hsin
Chao, Tze-Fan
Chen, Shao-Wei
Lee, Hsin-Fu
Yeh, Yung-Hsin
Huang, Ya-Chi
Chang, Shang-Hung
Kuo, Chi-Tai
Lip, Gregory Y. H.
Chen, Shih-Ann
[J]. HEART RHYTHM, 2020, 17 (12) : 2102 - 2110

← 1 2 3 4 5 →