Off-Label Use and Inappropriate Dosing of Direct Oral Anticoagulants in Cardiopulmonary Disease

被引：3
|
作者：
Hussein, Ayman A. [1 ]
Alvarez, Paulino [2 ]
Reed, Grant [3 ]
Heresi, Gustavo A. [4 ]
机构：
[1] Cleveland Clin, Dept Cardiovasc Med, Sect Cardiac Pacing & Electrophysiol, Cleveland, OH 44106 USA
[2] Cleveland Clin, Sect Heart Failure, Dept Cardiovasc Med, Cleveland, OH 44106 USA
[3] Cleveland Clin, Sect Intervent Cardiol, Dept Cardiovasc Med, Cleveland, OH 44106 USA
[4] Cleveland Clin, Dept Pulm & Crit Care Med, Cleveland, OH 44106 USA
来源：
CHEST | 2022年 / 161卷 / 05期
关键词：
direct oral anticoagulant; off-label use; thromboembolism; VALVULAR HEART-DISEASE; ATRIAL-FIBRILLATION; PULMONARY-HYPERTENSION; SINUS RHYTHM; ANTITHROMBOTIC THERAPY; VALVE THROMBOSIS; WARFARIN; FAILURE; OUTCOMES; STROKE;
D O I：
10.1016/j.chest.2022.01.033
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Direct oral anticoagulants (DOACs) are increasingly used in clinical practice and have become essential in the management of atrial fibrillation and VTE. The enthusiasm for DOACs has fueled the off-label application of these agents in cardiopulmonary disease, and their use has often outpaced the evidence supporting their application. This article reviews the evidence and current off-label use of DOACs in various cardiopulmonary disease states.
引用
收藏
页码：1360 / 1369
页数：10
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