Saccharomyces boulardii: a summary of the evidence for gastroenterology clinical practice in adults and children

被引:0
|
作者
Canani, R. Berni [1 ,2 ]
Cucchiara, S. [3 ]
Cuomo, R. [4 ]
Pace, F. [5 ,6 ]
Papale, F. [7 ]
机构
[1] Univ Naples Federico II, Dept Pediat, Naples, Italy
[2] Univ Naples Federico II, European Lab Invest Food Induced Dis, Naples, Italy
[3] Univ Roma La Sapienza, Dept Pediat, Rome, Italy
[4] Univ Naples Federico II, Dept Clin & Expt Med, Naples, Italy
[5] Univ Milan, Dept Clin Sci L Sacco, Seriate, BG, Italy
[6] Bolognini Hosp, Gastrointestinal Unit, Seriate, BG, Italy
[7] Zambon Italia, Bresso, MI, Italy
关键词
Probiotics; Acute gastroenteritis; Diarrhea; Irritable bowel disease; Inflammatory bowel diseases; Clostridium difficile; Antibiotic-associated diarrhea; Traveler's diarrhea; H. pylori infection; ANTIBIOTIC-ASSOCIATED DIARRHEA; DIFFERENT PROBIOTIC PREPARATIONS; BLASTOCYSTIS-HOMINIS INFECTION; CLOSTRIDIUM-DIFFICILE DISEASE; HELICOBACTER-PYLORI THERAPY; PLACEBO-CONTROLLED TRIAL; SMALL-BOWEL RESECTION; RAT SMALL-INTESTINE; BACTERIAL TRANSLOCATION; DOUBLE-BLIND;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Probiotics are viable, nonpathogenic microorganisms (bacteria or yeast) which when administered in adequate amounts, confer a health benefit on the host. At this time, Saccharomyces boulardii is the only yeast commonly used in clinical practice. Literature on this probiotic is wide and even more data become available each year. Thus, it could be problematic for a physician summarize all the best information deriving from basic research and clinical studies. With the aim to help physicians in the use of Saccharomyces boulardii, this paper focuses on the available evidences for its efficacy and safety in different diseases in adult and pediatric patients in order to provide a practical guidance for gastroenterology clinical practice. Indications and dosage for several gastrointestinal diseases for a correct use of this probiotic are provided, and recent insights on its mechanisms of action and possible future clinical application are also discussed.
引用
收藏
页码:809 / 822
页数:14
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