Further study of genetic association between the TNXB locus and schizophrenia

被引：4

作者：

Wang, Jiaoyan ^{[1
,2
,3
,4
]}

Sun, Shilong ^{[1
,2
]}

Zhang, Li ^{[3
,4
]}

Wang, Zhenqi ^{[1
,2
]}

Ye, Lin ^{[1
,2
]}

Liu, Linlin ^{[1
,2
]}

Wu, Ning ^{[1
,2
]}

Li, Heyao ^{[1
,2
]}

Zhang, Xuan ^{[1
,2
,3
,4
]}

Wu, Jiang ^{[3
,4
]}

机构：

[1] Jilin Univ, Sch Publ Hlth, Res Ctr Genom Med, Changchun 130021, Peoples R China

[2] Jilin Univ, Sch Publ Hlth, MH Radiobiol Res Unit, Changchun 130021, Peoples R China

[3] Jilin Univ, Hosp 1, Neurosci Res Ctr, Changchun 130021, Peoples R China

[4] Jilin Univ, Hosp 1, Dept Neurol, Changchun 130021, Peoples R China

来源：

PSYCHIATRIC GENETICS | 2011年 / 21卷 / 04期

关键词：

POPULATION;

D O I：

10.1097/YPG.0b013e3283413398

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Wei and Hemmings (2004) genotyped four single nucleotide polymorphisms in the TNXB locus among 122 British family trios of schizophrenia, and found that two closely linked coding single nucleotide polymorphisms were associated with schizophrenia, that is, rs1009382 and rs204887. The TNXB finding was replicated with a case- control study in a Japanese population (Tochigi et al., 2007), but failed to be replicated with a family-based study in a Chinese population (Liu et al., 2004). This study was then designed to re-validate the TNXB association by combining both family trios and case-control samples. © 2011 Wolters Kluwer Health | Lippincott Williams &Wilkins.

引用

页码：216 / 216

页数：1

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