Facile one-pot multicomponent synthesis of highly functionalized tetrahydropyridines using thiamine hydrochloride as an organocatalyst

被引:9
|
作者
Singh, Sandeep [1 ]
Gupta, Annah [1 ]
Kapoor, Kamal K. [1 ]
机构
[1] Univ Jammu, Dept Chem, Jammu, India
关键词
beta-Ketoester; tetrahydropyridine multicomponent; thiamine hydrochloride; VitB(1); ECONOMIC PASE SYNTHESIS; PIPERIDINE SCAFFOLDS; GRAPHENE OXIDE; DERIVATIVES; EFFICIENT; CATALYST; ATOM; COMPONENT; NITRATE;
D O I
10.1080/00397911.2020.1731756
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Thiamine hydrochloride (VitB(1)) has been found to be an efficient catalyst for the multicomponent synthesis of highly functionalized tetrahydropyridines from the reaction of beta-ketoester, aromatic aldehydes and anilines. VitB(1) is easily available, cheap, and eco benign. [GRAPHICS] .
引用
收藏
页码:1056 / 1063
页数:8
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