IAPP boosts islet macrophage IL-1 in type 2 diabetes

被引：30
|
作者：
Mandrup-Poulsen, Thomas [1 ,2 ,3 ]
机构：
[1] Univ Copenhagen, Dept Biomed Sci, Copenhagen, Denmark
[2] Hagedorn Res Inst, Gentofte, Denmark
[3] Karolinska Inst, Dept Med & Surg, Stockholm, Sweden
来源：
NATURE IMMUNOLOGY | 2010年 / 11卷 / 10期
关键词：
OXIDATIVE STRESS; INTERLEUKIN-1; ACTIVATION; MELLITUS; PROTEIN;
D O I：
10.1038/ni1010-881
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
IAPP, a hormone secreted together with insulin and deposited in pancreatic islets in type 2 diabetes, can induce macrophage processing of interleukin 1 linked to beta-cell destruction in type 2 diabetes.
引用
收藏
页码：881 / 883
页数：4
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