Visible-Light-Induced, Base-Promoted Transition-Metal-Free Dehalogenation of Aryl Fluorides, Chlorides, Bromides, and Iodides

被引：39
|
作者：
Ding, Ting-Hui [2 ]
Qu, Jian-Ping [1 ]
Kang, Yan-Biao [2 ]
机构：
[1] Nanjing Tech Univ, Inst Adv Synth, Sch Chem & Mol Engn, Nanjing 211816, Peoples R China
[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
来源：
ORGANIC LETTERS | 2020年 / 22卷 / 08期
基金：
中国国家自然科学基金;
关键词：
UNACTIVATED ALKYL; HALIDES; REDUCTION; HYDRODEHALOGENATION; CATALYST; ALKENYL;
D O I：
10.1021/acs.orglett.0c00827
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report a simple and efficient visible-light-induced transition-metal-free hydrogenation of aryl halides. The combined visible light and base system is used to initiate the desired radical-mediated hydrogenation. A variety of aryl fluorides, chlorides, bromides, and iodides could be reduced to the corresponding (hetero)arenes with excellent yields under mild conditions. Various functional groups and other heterocyclic compounds are tolerated.
引用
收藏
页码：3084 / 3088
页数：5
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