Alcohol dependence;
Alcohol use disorder;
Comorbidity;
Psychiatric illness;
Dual diagnosis;
D O I:
10.1186/s43045-019-0010-y
中图分类号:
R749 [精神病学];
学科分类号:
100205 ;
摘要:
Background Many international studies have reported a high prevalence of psychiatric comorbidity in alcohol-dependent individuals and highlighted the clinical, prognostic, and treatment implications of such findings. However, there is a paucity of such information within the context of India. This study investigates the prevalence of psychiatric comorbidity in treatment-seeking alcohol-dependent individuals and its relationship with the severity of this dependence. Result This was a prevalence study conducted for a period of 1 year. Patients were identified from Mahbubnagar, a local area in rural south India, and recruited at outpatient deaddiction clinic of SVS hosital. Application for research ethics approval was approved. A consecutive sample of 100 inpatients diagnosed with alcohol dependence syndrome was recruited. The Mini-International Neuropsychiatric Interview was used to assess psychiatric comorbidity 2 weeks after detoxification. The severity of dependence was judged using the Severity of Alcohol Dependence questionnaire. One-hundred (male, n = 65; female, n = 35) alcohol-dependent patients were recruited. The mean age of participants was 41.9 (SD = 9.3) years. Participants (n = 33, 33%) had a co-occurring psychiatric disorder, the commonest being mood disorder (n = 18), which sub-divided into major depressive disorder (n = 8), dysthymia (n = 5), manic episode (n = 3), and hypomanic episode (n = 2), followed by anxiety disorders (n = 11) and then psychotic disorder (n = 4). The comorbid psychiatric disorders were significantly associated with the severity of dependence (p = 0.001) and longer duration of alcohol (p = 0.003) use. Conclusion This result emphasizes the need to thoroughly assess patients for possible under-identified dual diagnosis and provide treatments accordingly.
机构:
King Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, IndiaKing Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, India
Das, Anamika
Kar, Sujita Kumar
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机构:
King Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, IndiaKing Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, India
Kar, Sujita Kumar
Gupta, Pawan Kumar
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机构:
King Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, IndiaKing Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, India
Gupta, Pawan Kumar
Dalal, Pronob Kumar
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机构:
King Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, IndiaKing Georges Med Univ, Dept Psychiat, Lucknow 226003, Uttar Pradesh, India
机构:
Taipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Chang, Hu-Ming
Pan, Chun-Hung
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机构:
Taipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Natl Chengchi Univ, Dept Psychol, Taipei, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Pan, Chun-Hung
Chen, Pao-Huan
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机构:
Taipei Med Univ, Coll Med, Sch Med, Dept Psychiat, Taipei, Taiwan
Taipei Med Univ Hosp, Psychiat Res Ctr, Taipei, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Chen, Pao-Huan
Chen, Yi-Lung
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机构:
Natl Sun Yat Sen Univ, Dept Biol Sci, Kaohsiung, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Chen, Yi-Lung
Tai, Ming-Hong
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机构:
Natl Sun Yat Sen Univ, Dept Biol Sci, Kaohsiung, Taiwan
Natl Sun Yat Sen Univ, Inst Biomed Sci, Kaohsiung, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Tai, Ming-Hong
Su, Sheng-Siang
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机构:
Taipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Su, Sheng-Siang
Tsai, Shang-Ying
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机构:
Taipei Med Univ, Coll Med, Sch Med, Dept Psychiat, Taipei, Taiwan
Taipei Med Univ Hosp, Psychiat Res Ctr, Taipei, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Tsai, Shang-Ying
Chen, Chiao-Chicy
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机构:
Taipei Med Univ, Coll Med, Sch Med, Dept Psychiat, Taipei, Taiwan
Taipei Med Univ Hosp, Psychiat Res Ctr, Taipei, Taiwan
Mackay Mem Hosp, Dept Psychiat, Taipei, Taiwan
Mackay Med Coll, Dept Psychiat, Taipei, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Chen, Chiao-Chicy
Kuo, Chian-Jue
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机构:
Taipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan
Taipei Med Univ, Coll Med, Sch Med, Dept Psychiat, Taipei, Taiwan
Taipei Med Univ Hosp, Psychiat Res Ctr, Taipei, TaiwanTaipei City Hosp, Taipei City Psychiat Ctr, Taipei 110, Taiwan