Ruthenium-catalyzed N-alkylation of amino-1,3,5-triazines using alcohols

被引：0
|
作者：
Zhao, Junna [1 ]
Zhong, Pengzhen [1 ]
Xie, Zhongpao [1 ]
Zhou, Wei [1 ]
Zhang, Chen [2 ]
Cui, Dong-Mei [1 ]
机构：
[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China
[2] Zhejiang Univ, Sch Pharmaceut Sci, Hangzhou 310058, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2021年 / 45卷 / 35期
关键词：
BORROWING HYDROGEN; DEHYDROGENATION; DESIGN;
D O I：
10.1039/d1nj03116c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient ruthenium-catalyzed N-alkylation of amino 1,3,5-triazines with alcohols was achieved via a BH/HA strategy. Following this simple, facile, and high atom economical protocol, a broad range of products was prepared in moderate to good yields and heterocyclic or benzylic alcohols containing various functionalities were tolerated. The application of the reaction is also further demonstrated by the synthesis of alkylated secondary amine-1,3,5-triazines from olefinated amino-1,3,5-triazines and alcohols via a one pot N-alkylation and reductive reactions.
引用
收藏
页码：15776 / 15779
页数：4
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