Mapping quantitative trait loci in humans: achievements and limitations

被引:22
|
作者
Majumder, PP [1 ]
Ghosh, S [1 ]
机构
[1] Indian Stat Inst, Human Genet Unit, Kolkata 700108, W Bengal, India
来源
JOURNAL OF CLINICAL INVESTIGATION | 2005年 / 115卷 / 06期
关键词
D O I
10.1172/JCI24757
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Recent advances in statistical methods and genomic technologies have ushered in a new era in mapping clinically important quantitative traits. However, many refinements and novel statistical approaches are required to enable greater successes in this mapping. The possible impact of recent findings pertaining to the structure of the human genome on efforts to map quantitative traits is yet unclear.
引用
收藏
页码:1419 / 1424
页数:6
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