Synthesis of Indolo[1,2-a]Quinoxalines via a Pd-Catallyzed Regioselective C-H Olefination/Cyclization Sequence

被引：75
|
作者：
Wang, Liang [1 ]
Guo, Wei [1 ]
Zhang, Xiao-Xiao [1 ]
Xia, Xu-Dong [1 ]
Xiao, Wen-Jing [1 ,2 ]
机构：
[1] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 03期
基金：
美国国家科学基金会;
关键词：
BOND FORMATION; SULFUR YLIDES; CATALYTIC FUNCTIONALIZATION; OXIDATIVE OLEFINATION; AROMATIC-SUBSTITUTION; BIOLOGICAL EVALUATION; DIRECT ARYLATION; BENZOIC-ACIDS; PALLADIUM; CASCADE;
D O I：
10.1021/ol203275b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly efficient approach to indolo [1,2-a]quinoxaline derivatives through a Pd-catalyzed regioselective C-H olefination/cyclization sequence has been developed. This transformation has a wide range of substrates with various functional groups, and the corresponding heterocyclic products were obtained in good yields.
引用
收藏
页码：740 / 743
页数：4
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