Precise measurement and control of the pressure-driven flows for microfluidic systems

被引：4
|
作者：
Zeng, Wen [1 ]
Fu, Hai [1 ]
机构：
[1] Harbin Inst Technol, Dept Fluid Control & Automat, Harbin 150001, Peoples R China
来源：
ELECTROPHORESIS | 2020年 / 41卷 / 10-11期
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
Closed-loop control; Flow rates; Microfluidic system; Pressure-driven flows; DROPLET; GENERATION;
D O I：
10.1002/elps.201900103
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The pressure-driven device is designed and the flow rates of the microfluidic systems can be supplied by the pressure-driven flows, which can significantly reduce the flow-rate fluctuations coming from the pump source. For pressure-driven flows, the flow rates of the fluids can be predicted by measuring the pressure drop along a polytetrafluoroethylene (PTFE) tubing. Especially, by varying the geometrical parameters of the PTFE tubing, the predicted flow rates of the fluids are compared with the experimental measurements, and the testing precision of the pressure-driven flows can be obtained. Meanwhile, the dynamic characteristics of the open-loop and closed-loop control pressure-driven device are comparatively studied. Particularly, a proportional and integral (PI) controller is integrated with the closed-loop control pressure-driven device, and the effects of the parameters of the PI controller on the dynamic characteristics of the pressure-driven devices are mainly discussed. Most importantly, by improving the dynamic characteristics of the pressure-driven devices, precise measurement and control of the pressure-driven flows can be achieved for microfluidic systems.
引用
收藏
页码：852 / 859
页数：8
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