DNA Markers from Genome-Wide Association Studies of Cardiovascular Diseases

被引：1
|
作者：
Khrunin, A. V. [1 ]
Aliev, A. M. [2 ]
Limborska, S. A. [1 ]
机构：
[1] Russian Acad Sci, Inst Mol Genet, Moscow 123182, Russia
[2] Univ Amsterdam, NL-1012 WX Amsterdam, Netherlands
来源：
MOLECULAR GENETICS MICROBIOLOGY AND VIROLOGY | 2018年 / 33卷 / 04期
关键词：
cardiovascular diseases; single nucleotide polymorphism; coronary artery disease; coronary heart disease; ischemic stroke; RISK;
D O I：
10.3103/S0891416818040031
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This paper presents the results of selecting the most promising single nucleotide polymorphisms associated with cardiovascular diseases in genome-wide association studies. Twenty such loci were identified. For eight of those loci, protocols for discrimination of the corresponding allelic variants with a real-time polymerase chain reaction (TaqMan) were developed and used for genotyping a sample of Russian individuals from Moscow.
引用
收藏
页码：245 / 247
页数：3
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