Innate Immunity: ER Stress Recruits NOD1 and NOD2 for Delivery of Inflammation

被引：15
|
作者：
Caruso, Roberta
Nunez, Gabriel [1 ]
机构：
[1] Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA
来源：
CURRENT BIOLOGY | 2016年 / 26卷 / 12期
关键词：
IV SECRETION SYSTEM; NF-KAPPA-B; PEPTIDOGLYCAN;
D O I：
10.1016/j.cub.2016.05.021
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
NOD1 and NOD2, two members of the intracellular NOD-like receptor family, sense bacterial peptidoglycan-derived fragments and induce pro-inflammatory responses. Recent work provides evidence for a role for NOD1/NOD2 signaling in mediating ER-stress-induced inflammatory responses via a peptidoglycan-independent mechanism.
引用
收藏
页码：R508 / R511
页数：4
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