Cyclic di-GMP in Streptomycetes: A New Conformation, New Binding Mode, New Receptor, and a New Mechanism to Control Cell Development

被引：7
|
作者：
Chou, Shan-Ho [1 ,2 ,3 ]
Galperin, Michael Y. [4 ]
机构：
[1] Huazhong Agr Univ, Coll Life Sci & Technol, State Key Lab Agr Microbiol, Wuhan 430070, Hubei, Peoples R China
[2] Natl Chung Hsing Univ, Inst Biochem, Taichung 40227, Taiwan
[3] Natl Chung Hsing Univ, Agr Biotechnol Ctr, Taichung 40227, Taiwan
[4] NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20894 USA
来源：
MOLECULAR CELL | 2020年 / 77卷 / 03期
关键词：
D O I：
10.1016/j.molcel.2020.01.018
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A recent paper by Gallagher et al. (2020) demonstrates that c-di-GMP controls spore formation in Streptomyces venezuelae through sequestering the sporulation sigma factor sigma(WhiG) and presents the crystal structure of a ternary complex between c-di-GMP, sigma(WhiG), and its anti-sigma factor, RsiG.
引用
收藏
页码：443 / 445
页数：3
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