Visible-light-induced intramolecular sp3 C-H oxidation of 2-alkyl-substituted benzamides for the synthesis of functionalized iminoisobenzofurans

被引：14
|
作者：
Wu, Lingang [1 ]
Hao, Yanan [1 ]
Liu, Yuxiu [1 ]
Wang, Qingmin [1 ,2 ]
机构：
[1] Nankai Univ, Coll Chem, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
[2] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 92期
基金：
中国国家自然科学基金;
关键词：
BOND-DISSOCIATION ENERGIES; PHOTOREDOX CATALYSIS; ASYMMETRIC ALKYLATION; ELECTRON-TRANSFER; RADICALS; AMINATION; ISOBENZOFURAN; CYCLIZATION; AMIDYL;
D O I：
10.1039/c9cc07791j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We have developed a protocol for the synthesis of functionalized iminoisobenzofurans by means of visible-light-induced intramolecular cyclization reactions of 2-alkyl-substituted benzamides. This one step-economical protocol, which involves intramolecular sp(3) C-O bond formation, features mild reaction conditions, exclusive chemoselectivity, and high yields.
引用
收藏
页码：13908 / 13911
页数：4
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