Molluscicidal saponins from Sapindus mukorossi, inhibitory agents of golden apple snails, Pomacea canaliculata

被引:80
|
作者
Huang, HC
Liao, SC
Chang, FR
Kuo, YH
Wu, YC
机构
[1] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung, Taiwan
[2] Tzu Hui Inst Technol, Dept Nursing, Nan Zhou, Ping Tung Count, Taiwan
[3] Natl Res Inst Chinese Med, Taipei, Taiwan
关键词
Sapindus mukorossi; Sapindaceae; molluscicidal effects; Pomacea canaliculata; hederagenin saponins;
D O I
10.1021/jf0301910
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
Extracts of soapnut, Sapindus mukorossi Gaertn. (Sapindaceae) showed molluscicidal effects against the golden apple snail, Pomacea canaliculata Lamarck. (Ampullariidae) with LC50 values of 85, 22, and 17 ppm after treating 24, 48, and 72 h, respectively. Bioassay-directed fractionation of S. mukorossi resulted in the isolation of one new hederagenin-based acetylated saponin, hederagenin 3-O-(2,4-O-di-acetyl-alpha-L-arabinopyranoside)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside (1), along with six known hederagenin saponins, hederagenin 3-O-(3,4-O-di-acetyl-alpha-L-arabinopyranoside)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside (2), hederagenin 3-O-beta-aacetyl-alpha-D-xylopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside (3), hederagenin 3-O-(4-O-acetyl-beta-D-xylopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside (4), hederagenin 3-O-(3,4-O-di-acetyl-beta-D-xylopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside (5), hederagenin 3-beta-D-xylopyranosyl-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside (6), and hederagenin 3-O-alpha-L-arabinopyranoside (7). The bioassay data revealed that 1-7 were molluscicidal, causing 70-100% mortality at 10 ppm against the golden apple snail.
引用
收藏
页码:4916 / 4919
页数:4
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