Thymoquinone, a bioactive phytochemical alleviates colon inflammation through Nrf2/Keap1 system: An experimental study using both in vivo and in vitro model of colon inflammation

被引：0
|
作者：
Subramanya, Sandeep B.
Venkataraman, Balaji
Raj, Vishnu
Al Marzooqi, Saeeda
Alhassani, Abdullah
AlHassani, Ahmed
Ahmed, Khadija Jamal
Attoub, Samir
机构：
来源：
FASEB JOURNAL | 2019年 / 33卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
764.2
引用
收藏
页数：3
相关论文
共 36 条
  • [21] Caesalpinia sappan Linn. Ameliorates Allergic Nasal Inflammation by Upregulating the Keap1/Nrf2/HO-1 Pathway in an Allergic Rhinitis Mouse Model and Nasal Epithelial Cells
    Pyun, Bo-Jeong
    Jo, Kyuhyung
    Lee, Joo Young
    Lee, Ami
    Jung, Myung-A
    Hwang, Youn-Hwan
    Jung, Dong Ho
    Ji, Kon-Young
    Choi, Susanna
    Kim, Yun Hee
    Kim, Taesoo
    ANTIOXIDANTS, 2022, 11 (11)
  • [22] L-carnitine regulated Nrf2/Keap1 activation in vitro and in vivo and protected oxidized fish oil-induced inflammation response by inhibiting the NF-κB signaling pathway in Rhynchocypris lagowski Dybowski
    Zhang, Dong-Ming
    Guo, Zhi-Xin
    Zhao, Yun-Long
    Wang, Qiu-Ju
    Gao, Yong-Sheng
    Yu, Ting
    Chen, Yu-Ke
    Chen, Xiu-Mei
    Wang, Gui-Qin
    FISH & SHELLFISH IMMUNOLOGY, 2019, 93 : 1100 - 1110
  • [23] Sinomenine Ameliorates IL-1β-Induced Intervertebral Disc Degeneration in Rats Through Suppressing Inflammation and Oxidative Stress via Keap1/Nrf2/NF-κB Signaling Pathways
    Lu, Gongbiao
    Zhang, Cunxin
    Li, Kang
    Gao, Kai
    Fu, Maoqing
    Lyu, Chaoliang
    Quan, Zhengxue
    JOURNAL OF INFLAMMATION RESEARCH, 2023, 16 : 4777 - 4791
  • [24] Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling
    Wang, Mengyuan
    Li, Bo
    Liu, Yijiang
    Zhang, Mengting
    Huang, Caoxin
    Cai, Teng
    Jia, Yibing
    Huang, Xiaoqing
    Ke, Hongfei
    Liu, Suhuan
    Yang, Shuyu
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [25] Salvianolic Acid C against Acetaminophen-Induced Acute Liver Injury by Attenuating Inflammation, Oxidative Stress, and Apoptosis through Inhibition of the Keap1/Nrf2/HO-1 Signaling
    Wu, Chien-Ta
    Deng, Jeng-Shyan
    Huang, Wen-Chin
    Shieh, Po-Chou
    Chung, Mei-Ing
    Huang, Guan-Jhong
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2019, 2019
  • [26] Epigallocatechin gallate potentially abrogates fluoride induced lung oxidative stress, inflammation via Nrf2/Keap1 signaling pathway in rats: An in-vivo and in-silico study (vol 39, pg 128, 2016)
    Shanmugam, Thangapandiyan
    Selvaraj, Miltonprabu
    Poomalai, Senthilraja
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 80
  • [27] Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway (vol 18, pg 124, 2018)
    Zhao, Xiao-Juan
    Yu, Han-Wen
    Yang, Yan-Zi
    Wu, Wen-Yuan
    Chen, Tian-Yu
    Jia, Ke-Ke
    Kang, Lin-Lin
    Jiao, Rui-Qing
    Kong, Ling-Dong
    REDOX BIOLOGY, 2019, 22
  • [28] RETRACTION: Preventive Electroacupuncture Alleviates Oxidative Stress and Inflammation via Keap1/Nrf2/HO-1 Pathway in Rats with Cyclophosphamide-Induced Premature Ovarian Insufficiency (Retraction of Vol 2022, art no 6718592, 2022)
    Chen, Y.
    Zhao, R.
    Li, X.
    BIOMED RESEARCH INTERNATIONAL, 2023, 2023
  • [29] Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo experimental models
    Puppala, Eswara Rao
    Jain, Siddhi
    Saha, Pritam
    Rachamalla, Mahesh
    Syamprasad, N. P.
    Yalamarthi, Sai Sudha
    Abubakar, Md.
    Chaudhary, Antra
    Chamundeswari, D.
    Murty, U. S. N.
    Gangasani, Jagadeesh Kumar
    Naidu, V. G. M.
    PHYTOMEDICINE, 2022, 97
  • [30] Moderate Hypothermia Alleviates Sepsis-Associated Acute Lung Injury by Suppressing Ferroptosis Induced by Excessive Inflammation and Oxidative Stress via the Keap1/GSK3β/Nrf2/GPX4 Signaling Pathway
    Xu, Jie
    Tao, Liujun
    Jiang, Liangyan
    Lai, Jie
    Hu, Juntao
    Tang, Zhanhong
    JOURNAL OF INFLAMMATION RESEARCH, 2024, 17 : 7687 - 7704
1234