Histopathological lesions in lead intoxicated dogs

被引：0
|
作者：
Papaioannou, N [1 ]
Vlemmas, I [1 ]
Balaskas, N [1 ]
Tsangaris, T [1 ]
机构：
[1] Aristotelian Univ Salonika, Pathol Lab, Fac Vet Med, GR-54006 Salonika, Greece
来源：
VETERINARY AND HUMAN TOXICOLOGY | 1998年 / 40卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
The ultrastructural lesions of lead poisoning and the deposition of lead in liver, kidney, peritoneum, cerebellum and retina of dogs were studied. Specimens were obtained from 5 3-4 mo-old cross-breed dogs each injected ip with a total dose of 120 mg lead acetate, divided in 10 equal doses of 12 mg,administered every other day. Two dogs were controls. Histopathological examination revealed degeneration of the epithelial cells of the urinary tubules, the endothelial cells of the renal capillaries and the hepatocytes. Characteristics lead inclusion bodies were observed intracytoplasmically in the interstitial connective tissue cells of the kidney, and substancial quantities of the lead were in collagen fibers of the interstitial kidney tissue.
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页码：203 / 207
页数：5
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