CD70 is a novel therapeutic target for EGFR mutant NSCLC with acquired, EMT-associated EGFR TKI resistance

被引:0
|
作者
Nilsson, Monique B. [1 ]
Yang, Yan [1 ]
Patel, Sonia [1 ]
Heeke, Simon [1 ]
Le, Xiuning [1 ]
Aruguman, Thiru [1 ]
Robichaux, Jacqulyne [1 ]
Yu, Xiaoxing [1 ]
Poteete, Alissa [1 ]
Ren, Xiaoyang [1 ]
Diao, Lixia [1 ]
Shen, Li [1 ]
Wang, Qi [1 ]
Zhang, Fahao [1 ]
Clemente, Leticia Campos [1 ]
Soto, Luisa Solis [1 ]
Shi, Chunhua [1 ]
Tran, Hai [1 ]
Bock, Jason [1 ]
Wang, Jing [1 ]
Wistuba, Ignacio I. [1 ]
Minna, John D. [2 ]
Heymach, John V. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX USA
[2] Univ Texas SouthWestern Med Ctr, Dallas, TX USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1827
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Response to pemetrexed rechallenge after acquired resistance of EGFR-TKI in a patient with advanced NSCLC
    Li, Shuai
    Zhou, Fangyu
    Ren, Shengxiang
    Zhou, Caicun
    LUNG CANCER, 2014, 84 (02) : 203 - 205
  • [32] Wnt Signal Pathway and EMT Gene Expressions Are Possible Mechanisms of Acquired Resistance of EGFR-TKI
    Xu, X.
    Lee, J. C.
    Chung, J-H
    LABORATORY INVESTIGATION, 2010, 90 : 415A - 415A
  • [33] Wnt Signal Pathway and EMT Gene Expressions Are Possible Mechanisms of Acquired Resistance of EGFR-TKI
    Xu, X.
    Lee, J. C.
    Chung, J-H
    MODERN PATHOLOGY, 2010, 23 : 415A - 415A
  • [34] Cigarette smoke extract exposure induces EGFR-TKI resistance in EGFR-mutated NSCLC via mediating Src activation and EMT
    Li, Dandan
    Zhang, Lu
    Zhou, Junhao
    Chen, Hong
    LUNG CANCER, 2016, 93 : 35 - 42
  • [35] Cigarette Smoke Extract Exposure Induces EGFR-Tki Resistance In EGFR-Mutated Nsclc Via Mediating Src Activation And Emt
    Chen, H.
    Li, D.
    Zhang, L.
    Zhou, J.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
  • [36] Honokiol, a natural product, overcomes acquired resistance of EGFR mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib
    Zang, Hongjing
    Fan, Songqing
    Arbiser, Jack
    Owonikoko, Taofeek K.
    Ramalingam, Suresh S.
    Sun, Shi-Yong
    CANCER RESEARCH, 2019, 79 (13)
  • [37] LOSS OF AMPLIFIED EGFR GENE WITH MUTATION AS A NOVEL MECHANISM OF ACQUIRED RESISTANCE TO EGFR-TKIS IN EGFR MUTATED NSCLC CELLS
    Furugaki, K.
    Iwai, T.
    Moriya, Y.
    Fujimoto-Ouchi, K.
    ANNALS OF ONCOLOGY, 2012, 23 : 390 - 391
  • [38] Is CD73 Expression a Druggable Mechanism of Resistance in EGFR-TKI-Treated EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC)?
    Eide, I. J.
    Dyrbekk, A. P.
    Helland, A.
    Ekman, S.
    Koivunen, J.
    Cicenas, S.
    Gronberg, B.
    Bisha, I.
    Haberichter, T.
    Lakis, S.
    Chan, J.
    Lewis, A.
    Martin, P.
    Cooper, Z.
    Brustugun, O. T.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S1154 - S1154
  • [39] Evolution of MET and NRAS gene amplification as acquired resistance mechanisms in EGFR mutant NSCLC
    Peters, T. L.
    Patil, T.
    Le, A. T.
    Davies, K. D.
    Brzeskiewicz, P. M.
    Nijmeh, H.
    Bao, L.
    Camidge, D. R.
    Aisner, D. L.
    Doebele, R. C.
    NPJ PRECISION ONCOLOGY, 2021, 5 (01)
  • [40] Evolution of MET and NRAS gene amplification as acquired resistance mechanisms in EGFR mutant NSCLC
    T. L. Peters
    T. Patil
    A. T. Le
    K. D. Davies
    P. M. Brzeskiewicz
    H. Nijmeh
    L. Bao
    D. R. Camidge
    D. L. Aisner
    R. C. Doebele
    npj Precision Oncology, 5