An elastography analytical method for the rapid detection of endotoxin

被引:11
|
作者
Sun, Haixuan [1 ,2 ,3 ]
Miao, Peng [1 ,3 ]
Tang, Yuguo [1 ,3 ]
Wang, Bidou [1 ]
Qian, Jun [1 ]
Wang, Danyi [1 ]
机构
[1] Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, CAS Key Lab Bio Med Diagnost, Suzhou, Peoples R China
[2] Chinese Acad Sci, Changchun Inst Opt Fine Mech & Phys, Changchun, Peoples R China
[3] Univ Chinese Acad Sci, Beijing, Peoples R China
基金
中国国家自然科学基金;
关键词
LIMULUS AMEBOCYTE LYSATE; BACTERIAL-ENDOTOXIN; ASSAY; SENSOR; LIPOPOLYSACCHARIDE; VALIDATION; APTASENSOR; CELLS;
D O I
10.1039/c5an00734h
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We present a flexible analytical method for the study of coagulation systems by monitoring elastography (EG). The rapid detection of endotoxin is achieved by the EG analysis of endotoxin-induced limulus amebocyte lysate coagulation. This method is superior to other methods using the same reagents in not only sensitivity but also detecting time.
引用
收藏
页码:4374 / 4378
页数:5
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