Neo-adjuvant chemotherapy followed by radical resection for primary borderline resectable unicentric Castleman disease: a case report

被引：0
|
作者：
Zhuang, Hongkai [1 ,2 ]
Ma, Zuyi [1 ,2 ]
Wu, Yanxia [3 ]
Yin, Zi [1 ]
Jian, Zhixiang [1 ]
Zhang, Chuanzhao [1 ]
Hou, Baohua [1 ]
机构：
[1] Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Gen Surg, 106 Zhongshan Er Rd, Guangzhou 510080, Peoples R China
[2] Shantou Univ, Med Coll, Shantou 515000, Peoples R China
[3] Sun Yat Sen Univ, Sch Med, Guangzhou 510080, Peoples R China
来源：
TRANSLATIONAL CANCER RESEARCH | 2020年 / 9卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Castleman disease; neo-adjuvant chemotherapy; plasma cell type; case report;
D O I：
10.21037/tcr.2020.02.45
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Here we introduced a successful case showing neo-adjuvant chemotherapy followed by radical resection for a borderline resectable unicentric Castleman disease (UCD). This study demonstrated that neo-adjuvant rituximab in combination with cyclophosphamide, epirubicin, vincristine and prednisone (R-CHOP) chemotherapy alleviated the symptom of plasma cell type of Castleman disease (PCCD) as well as downsized the tumor to provide an opportunity for radical surgical resection. It would contribute to the treatment for borderline resectable or unresectable UCD in the future.
引用
收藏
页码：3030 / 3033
页数：4
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