Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF)

被引：134
|
作者：
Mitchell, RA [1 ]
Bucala, R [1 ]
机构：
[1] Picower Inst Med Res, Manhasset, NY 11030 USA
来源：
SEMINARS IN CANCER BIOLOGY | 2000年 / 10卷 / 05期
关键词：
angiogenesis; MAP kinases; macrophage migration inhibitory factor; MIF; proliferation;
D O I：
10.1006/scbi.2000.0328
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
First identified nt al nearly 40 years ago, macrophage migration inhibitory factor (MIF) is a potent pro-inflammatory cytokine and is an essential component of immune and inflammatory responses. Recent studies suggest that MIF may also contribute to multiple aspects of tumor progression and neoplasia. This review will attempt to summarize these findings focusing on MIF's ability to modulate cell proliferation, tumor. angiogenesis and tumor suppressor activity.
引用
收藏
页码：359 / 366
页数：8
相关论文
共 50 条
  • [1] Tumor Growth-Promoting Properties of Macrophage Migration Inhibitory Factor
    Bifulco, Carlo
    McDaniel, Katy
    Leng, Lin
    Bucala, Richard
    CURRENT PHARMACEUTICAL DESIGN, 2008, 14 (36) : 3790 - 3801
  • [2] Involvement of macrophage migration inhibitory factor (MIF) in the mechanism of tumor cell growth
    Takahashi, N
    Nishihira, J
    Sato, Y
    Kondo, M
    Ogawa, H
    Ohshima, T
    Une, Y
    Todo, S
    MOLECULAR MEDICINE, 1998, 4 (11) : 707 - 714
  • [3] Involvement of Macrophage Migration Inhibitory Factor (MIF) in the Mechanism of Tumor Cell Growth
    Norihiko Takahashi
    Jun Nishihira
    Yuji Sato
    Masao Kondo
    Hideaki Ogawa
    Takahiro Ohshima
    Yoshie Une
    Satoru Todo
    Molecular Medicine, 1998, 4 : 707 - 714
  • [4] Neuroendocrine properties of macrophage migration inhibitory factor (MIF)
    Fingerle-Rowson, GR
    Bucala, R
    IMMUNOLOGY AND CELL BIOLOGY, 2001, 79 (04): : 368 - 375
  • [5] Neuroimmunomodulation by macrophage migration inhibitory factor (MIF)
    Bucala, R
    NEUROIMMUNOMODULATION: MOLECULAR ASPECTS, INTEGRATIVE SYSTEMS, AND CLINICAL ADVANCES, 1998, 840 : 74 - 82
  • [6] Macrophage migration inhibitory factor (MIF) - Its potential role in tumor growth and tumor-associated angiogenesis
    Nishihira, J
    Ishibashi, T
    Fukushima, T
    Sun, BL
    Sato, Y
    Todo, S
    TISSUE REMODELING, 2003, 995 : 171 - 182
  • [7] Mechanisms of macrophage migration inhibitory factor (MIF)-dependent tumor microenvironmental adaptation
    Rendon, Beatriz E.
    Willer, Sharon S.
    Zundel, Wayne
    Mitchell, Robert A.
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2009, 86 (03) : 180 - 185
  • [8] Macrophage migration inhibitory factor (MIF) in bronchial asthma
    Yamaguchi, E
    Nishihira, J
    Shimizu, T
    Takahashi, T
    Kitashiro, N
    Hizawa, N
    Kamishima, K
    Kawakami, Y
    CLINICAL AND EXPERIMENTAL ALLERGY, 2000, 30 (09): : 1244 - 1249
  • [9] MECHANISM OF ACTION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)
    PICK, E
    MANHEIMER, S
    INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 1973, 45 (1-2): : 295 - 298
  • [10] Macrophage migration inhibitory factor (MIF) & weight loss
    Church, T
    Willis, MS
    Priest, EL
    Giroir, BP
    Wilkinson, WJ
    Blair, SN
    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2004, 36 (05): : S151 - S151
12345