Benign Cerebellar Pilocytic Astrocytomas in Children

被引:0
|
作者
Bilginer, Burcak [1 ]
Narin, Firat [1 ]
Oguz, Kader Karli [2 ]
Uzun, Sennur [3 ]
Soylemezoglu, Figen [4 ]
Akalan, Nejat [1 ]
机构
[1] Hacettepe Univ, Sch Med, Dept Neurosurg, Ankara, Turkey
[2] Hacettepe Univ, Sch Med, Dept Radiol, Ankara, Turkey
[3] Hacettepe Univ, Sch Med, Dept Anaesthesiol & Reanimat, Ankara, Turkey
[4] Hacettepe Univ, Sch Med, Dept Pathol, Ankara, Turkey
关键词
Pilocytic astrocytoma; Cerebellum; Brain tumor; Childhood; Astrocytomas; FOLLOW-UP; CHILDHOOD; RECURRENCE;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
AIM: Cerebellar astrocytomas are benign tumors of the central nervous system. They represent 10% of all pediatric intracranial brain tumors and 30% of all pediatric posterior fossa tumors especially in the first two decades of life. MATERIAL and METHODS: Material and Methods: We reviewed the medical records of patients; age at the time of surgery, pre- and post operative magnetic resonance imaging (MRI), localisation of the tumor, hydrocephalus, surgical approach, pre- and post operative neurological status, post operative adjuvant therapy and outcome were documented. RESULTS: The male to female ratio was 20/11. Age at the time of evaluation ranged from 3 to 23 years. Age at the time of surgery ranged from 1 to 18 years. Follow-up duration after surgery was 1-12 years. 55% of these tumors were located at the cerebellar vermis and 45% were at the cerebellar hemispheres. Complete surgical resection was done in 74% of these patients. 5 patients had a second operation because of residual tumor. Ventriculoperitoneal shunt insertion was performed in 3 of 31 patients because of symptomatic hydrocephalus and 1 patient had an endoscopic third ventriculostomy pre-operatively. 90% of these patients had no neurological sequelae at follow-up evaluation. CONCLUSION: Cerebellar astrocytomas are benign tumors where total resection is possible in the majority of cases with an excellent outcome.
引用
收藏
页码:22 / 26
页数:5
相关论文
共 50 条
  • [31] CHEMOTHERAPY FOR PILOCYTIC ASTROCYTOMAS
    BROWN, MT
    FRIEDMAN, HS
    OAKES, WJ
    BOYKO, OB
    HOCKENBERGER, B
    SCHOLD, SC
    CANCER, 1993, 71 (10) : 3165 - 3172
  • [32] Eosinophils in Pilocytic Astrocytomas
    Rashidipour, Omid
    Wilson, Beverly
    Pugh, Jeffrey
    Mehta, Vivek
    Lu, Jian-Qiang
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2013, 72 (06): : 562 - 562
  • [33] Spontaneous modifications of contrast enhancement in childhood non-cerebellar pilocytic astrocytomas
    Simona Gaudino
    Francesca Romana Quaglio
    Chiara Schiarelli
    Matia Martucci
    Tommaso Tartaglione
    Maria Rosaria Gualano
    Giuseppe Maria Di Lella
    Cesare Colosimo
    Neuroradiology, 2012, 54 : 989 - 995
  • [34] UTILITY OF LONG TERM NEURO-IMAGING IN PATIENTS WITH CEREBELLAR PILOCYTIC ASTROCYTOMAS
    Klesse, Laura
    Bezner, Stephanie
    Gargan, Lynn
    Leonard, David
    Bowers, Daniel
    PEDIATRIC BLOOD & CANCER, 2011, 56 (06) : 963 - 963
  • [35] RECENT EXPERIENCE WITH CEREBELLAR ASTROCYTOMAS IN CHILDREN
    KATZ, M
    SHAPIRO, K
    SHULMAN, K
    CHILDS BRAIN, 1979, 5 (06): : 571 - 571
  • [36] QUANTITATIVE MICROSCOPIC ANALYSIS OF PILOCYTIC ASTROCYTOMAS OF THE OPTIC PATHWAY IN CHILDREN
    JULIS, I
    JULISOVA, I
    BENES, V
    SBORNIK LEKARSKY, 1988, 90 (01): : 26 - 29
  • [37] DNA methylation pattern of brain stem pilocytic astrocytomas in children
    Witt, H.
    Korshunov, A.
    Remke, M.
    Janzarik, W. G.
    Gnekow, A.
    Scheurlen, W.
    Kulozik, A. E.
    Lichter, P.
    Pfister, S.
    JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
  • [38] Pilocytic Astrocytomas of the Optic Nerve and Their Relation to Pilocytic Astrocytomas Elsewhere in the Central Nervous System
    Reis, G. F.
    Bloomer, M.
    Karnezis, A.
    Phillips, J.
    Goldhoff, P.
    Tihan, T.
    LABORATORY INVESTIGATION, 2012, 92 : 435A - 435A
  • [39] Pilocytic Astrocytomas of the Optic Nerve and Their Relation to Pilocytic Astrocytomas Elsewhere in the Central Nervous System
    Reis, G. F.
    Bloomer, M.
    Karnezis, A.
    Phillips, J.
    Goldhoff, P.
    Tihan, T.
    MODERN PATHOLOGY, 2012, 25 : 435A - 435A
  • [40] Pilocytic astrocytomas of the optic nerve and their relation to pilocytic astrocytomas elsewhere in the central nervous system
    Reis, Gerald F.
    Bloomer, Michele M.
    Perry, Arie
    Phillips, Joanna J.
    Grenert, James P.
    Karnezis, Anthony N.
    Tihan, Tarik
    MODERN PATHOLOGY, 2013, 26 (10) : 1279 - 1287