Direct phosphorylation of benzylic C-H bonds under transition metal-free conditions forming sp3C-P bonds

被引：4

作者：

Li, Qiang ^{[1
]}

Zhao, Chang-Qiu ^{[1
]}

Chen, Tieqiao ^{[2
]}

Han, Li-Biao ^{[2
,3
]}

机构：

[1] Liaocheng Univ, Coll Chem & Chem Engn, 1 Hunan Rd, Liaocheng 252059, Shandong, Peoples R China

[2] Hainan Univ, Key Lab Minist Educ Adv Mat Trop Isl Resources, Hainan Prov Key Lab Fine Chem, Hainan Prov Fine Chem Engn Res Ctr, Haikou 570228, Hainan, Peoples R China

[3] Zhejiang Yanfan New Mat Co Ltd, Shangyu 312369, Zhejiang, Peoples R China

来源：

RSC ADVANCES | 2022年 / 12卷 / 29期

关键词：

DEHYDROGENATIVE-COUPLING REACTIONS; RADICAL TANDEM CYCLIZATION; REGIOSELECTIVE PHOSPHONATION; ARYLBORONIC ACIDS; CATALYTIC AMOUNTS; EFFICIENT; FUNCTIONALIZATION; ACTIVATION; VERSATILE; AMINES;

D O I：

10.1039/d2ra02812c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Direct phosphorylation of benzylic C-H bonds was achieved in a biphasic system under transition metal-free conditions. A selective radical/radical sp(3)C-H/P(O)-H cross coupling was proposed, and various substituted toluenes were applicable. The transformation provided a promising method for constructing sp(3)C-P bonds.

引用

页码：18441 / 18444

页数：4

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