Stereoselective synthesis of alexine stereoisomers from (S)-pyroglutamic acid

被引：33
|
作者：
Ikota, N
Nakagawa, H
Ohno, S
Noguchi, K
Okuyama, K
机构：
[1] Natl Inst Radiol Sci, Inage Ku, Chiba 2638555, Japan
[2] Tokyo Univ Agr & Technol, Dept Biotechnol, Tokyo 1848588, Japan
来源：
TETRAHEDRON | 1998年 / 54卷 / 31期
关键词：
D O I：
10.1016/S0040-4020(98)00542-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Four stereoisomers or alexine (1,7a-diepialexine (1a), 1,7,7a-triepialexine (1b), 1-epi-alexine (30a), and 1,7-diepialexine (30b)), the polyhydroxylated pyrrolizidine alkaloid, were synthesized from (S)-pyroglutamic acid derivative (6). (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：8985 / 8998
页数：14
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