Synthesis of pentafluorophenylmethylamines via silicon Mannich reaction

被引：27
|
作者：
Dilman, AD
Belyakov, PA
Korlyukov, AA
Struchkova, MI
Tartakovsky, VA
机构：
[1] ND Zelinskii Inst Organ Chem, Moscow 119991, Russia
[2] AN Nesmeyanov Organoelement Cpds Inst, Moscow 119991, Russia
来源：
ORGANIC LETTERS | 2005年 / 7卷 / 14期
关键词：
D O I：
10.1021/ol050845l
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The three-component coupling of aldehydes, secondary amines, and methoxytris(pentafluorophenyl)silane, MeOSi(C6F5)(3), affording pentafluorophenylmethylamines has been described. The generation of the five-coordinate silicate intermediate is believed to be the key feature responsible for the efficiency of the reaction.
引用
收藏
页码：2913 / 2915
页数：3
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