A Rare Association of Celiac Disease and Aplastic Anemia: Case Report of a Child and Review of Literature

被引:8
|
作者
Badyal, Rama Kumari [1 ]
Sachdeva, Man Updesh Singh [1 ]
Varma, Neelam [1 ]
Thapa, Babu Ram [2 ]
机构
[1] Postgrad Inst Med Educ & Res, Dept Hematol, Chandigarh, India
[2] Postgrad Inst Med Educ & Res, Dept Pediat Gastroenterol, Chandigarh, India
关键词
aplastic anemia; celiac disease; child; gluten-free diet; MANIFESTATIONS; FOXP3(+);
D O I
10.2350/14-05-1489-CR.1
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
An association between severe aplastic anemia and other autoimmune diseases is rare and has been described in adults for eosinophilic fasciitis, thymomas, systemic lupus erythematosus, and thyroid disorders. Herein we report a patient with celiac disease who was not strictly following a gluten-free diet and presented with progressive pallor, fever, and weakness of 1 month's duration. On investigation, he had pancytopenia, which on subsequent evaluation revealed aplastic anemia. An association between aplastic anemia and celiac disease has rarely been reported. To the best of author's knowledge, only 1 pediatric case of celiac disease associated with aplastic anemia has been published. This is the second report to suggest such an association in children.
引用
收藏
页码:470 / 473
页数:4
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