Significance of aldosterone antagonist therapy

被引：4
|
作者：
Christ, M [1 ]
Grimm, W [1 ]
Maisch, B [1 ]
机构：
[1] Univ Marburg, Innere Med Klin, D-35033 Marburg, Germany
来源：
INTERNIST | 2004年 / 45卷 / 03期
关键词：
heart failure; hypertension; aldosterone; diuretics; mineralocorticoid receptor antagonism;
D O I：
10.1007/s00108-003-1087-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Seit der klinischen Einführung der ACE-Inhibitoren hat die zuvor über 30 Jahre praktizierte diuretische Therapie mit Aldosteronantagonisten ihren Stellenwert verloren. Aktuelle Studien zur Wirksamkeit von Aldosteronantagonisten (RALES und EPHESUS) bei Patienten mit chronischer Herzinsuffizienz bzw. nach akutem Myokardinfarkt führen zu einer Neubewertung. Ein „altes“ Konzept erlebt seine Renaissance in der Therapie kardiovaskulärer Erkrankungen.
引用
收藏
页码：347 / 354
页数：8
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