Synthesis, characterization and antimicrobial activity of palladium(II) complexes with O,O' -dialkyl esters of ( S,S )-ethylenediamine- N,N' -di-(3,3?-1H-indol-3yl)-propionic acid

被引：4
|
作者：
Milic, Sandra S. Jovicic [1 ]
Jevtic, Verica V. [1 ]
Stojkovic, Danijela Lj. [1 ,2 ]
Petrovic, Dorde S. [1 ]
Avdovic, Edina H. [1 ,2 ]
Markovic, Zoran S. [2 ]
Radojevic, Ivana D. [3 ]
Comic, Ljiljana [3 ]
Mladenovic, Violeta S. [4 ]
机构：
[1] Univ Kragujevac, Fac Sci, Dept Chem, Radoja Domanovica 12, Kragujevac 34000, Serbia
[2] Univ Kragujevac, Inst Informat Technol, Dept Sci, Kragujevac 34000, Serbia
[3] Univ Kragujevac, Fac Sci, Dept Biol & Ecol, Radoja Domanovica 12, Kragujevac 34000, Serbia
[4] Univ Kragujevac, Dept Internal Med, Fac Med Sci, Svetozara Markovica 69, Kragujevc 34000, Serbia
来源：
INORGANICA CHIMICA ACTA | 2020年 / 510卷
关键词：
STEREOSPECIFIC LIGANDS; ALKYL ESTERS; GROWTH;
D O I：
10.1016/j.ica.2020.119743
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A series of four new ligands of general formula R2-S,S-eddtrp·2HCl (L1–L4) and their palladium(II) complexes of general formula [PdCl2(R2-S,S-eddtrp)] (C1–C4) where R = ethyl, 1-propyl, 1-butyl and 1-pentyl; S,S-eddtrp·2HCl = ethylenediamine-N,N′-di-(3,3′-1H-indol-3yl)propionic acid dihydrochloride have been synthesized and characterized by elemental microanalysis, infrared, 1H and 13C NMR spectroscopy. The proposed structures of all compounds were examined by density functional theory (DFT). The ligands (L1–L4) and Pd(II) complexes (C1–C4) were screened for their antimicrobial activity against 19 microorganisms and minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) were determinated. All tested ligands and complexes exhibited the highest antimicrobial activity on Escherichia coli ATCC 25922, being in range or higher than positive control, tetracycline. © 2020 Elsevier B.V.
引用
收藏
页数：6
相关论文
共 50 条
  • [31] Synthesis, characterization and antimicrobial activity of 3,5-di-tert-butylsalicylaldehyde-S-methylthiosemicarbazones and their Ni(II) complexes
    Turkkan, Baki
    Sariboga, Bahtiyar
    Sariboga, Nezaket
    TRANSITION METAL CHEMISTRY, 2011, 36 (06) : 679 - 684
  • [32] Newly synthesized palladium(<sc>ii</sc>) complexes with dialkyl esters of (S,S)-propylenediamine-N,N′-di-(2,2′-di-(4-hydroxy-benzil))acetic acid: in vitro investigation of biological activities and HSA/DNA binding
    Corovic, Kemal
    Stojkovic, Danijela Lj.
    Petrovic, Dorde S.
    Milic, Sandra S. Jovicic
    Dukic, Maja B.
    Radojevic, Ivana D.
    Rakovic, Ivana
    Jurisevic, Milena
    Gajovic, Nevena
    Jovanovic, Marina
    Marinkovic, Jovana
    Jovanovic, Ivan
    Stojanovic, Bojan
    DALTON TRANSACTIONS, 2024, 53 (18) : 7922 - 7938
  • [33] STRUCTURES OF 1,3-DICYCLOHEXYL-1-(1H-INDOL-3-YLACETYL)UREA, C23H31N3O2(I), AND 3-CYCLOHEXYL-1-[2-(1H-INDOL-3-YL)ETHYL]UREA, C17H23N3O(II)
    ISHIDA, T
    YAMASHITA, M
    TAKAI, H
    INOUE, M
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1983, 39 (SEP) : 1294 - 1297
  • [34] Dipotassium di-μ-isothiocyanato-κ4N:S-bis[(N- salicylidene-DL-valinato-κ3O,N,O′)cuprate(II)]
    Vanco, J
    Svajlenová, O
    Marek, J
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 2003, 59 (05) : M190 - M192
  • [35] Tris(1H-benzimidazole-κN3)(thiodiacetato-κ3O,S,O′)cobalt(II) dihydrate
    Cao, L
    Liu, JG
    Xu, DJ
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2006, 62 : M579 - M581
  • [36] Tris(1H-benzimidazole-κN3)(thiodiacetato-κ3O, S, O')cadmium(II) dihydrate
    Pan, TT
    Xu, DJ
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2005, 61 : M1735 - M1737
  • [37] Tris(1H-imidazole-κN3)(thiodiacetato-κ3O,S,O′)-nickel(II) monohydrate
    Pan, TT
    Su, JR
    Xu, DJ
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : M1576 - M1578
  • [38] Complexes of the trioxodinitrate anion: Synthesis and characterization of [Zn-II(bipy)(H2O)(N2O3)] and [Co-II(bipy)(2)(N2O3)]
    Chuy, C
    Falvello, LR
    Libby, E
    SantaMaria, JC
    Tomas, M
    INORGANIC CHEMISTRY, 1997, 36 (10) : 2004 - 2009
  • [39] Bis{benzyl N′-[(1H-indol-3-yl)methylene]dithiocarbazato-κ2N′,S}copper( II) N, N-dimethylformamide disolvate
    Khaledi, Hamid
    Ali, Hapipah Mohd
    Ng, Seik Weng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : M139 - U272
  • [40] Crystal structure of (S)-2-amino-3-(1H-indol-3-yl)propanoic acidate - acetic acid - water (1:1:1), C11H12N2O2•CH3COOH•H2O
    Li, Jian
    Liang, Zu-Pei
    Tai, Xi-Shi
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2009, 224 (01): : 153 - 154
12345