The rebirth of a drug: Thalidomide

被引：0
|
作者：
Lima, LM
Fraga, CAM
Barreiro, EJ
机构：
[1] Univ Fed Rio de Janeiro, Inst Quim, Dept Quim Organ, BR-21944970 Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Fac Farm, Dept Farm, BR-21944970 Rio De Janeiro, Brazil
来源：
QUIMICA NOVA | 2001年 / 24卷 / 05期
关键词：
thalidomide; rebirth of an old drug; leprosy;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Thalidomide, first synthesized in 1953, was widely prescribed I-or morning sickness of pregnant women from 1957 to 1961, when it was found to be seriously teratogenic, having caused serious birth defect. Nowadays, a quarter Of a Century later, it appears that it may be a miracle drug for such diseases as leprosy, AIDS, cancer and tuberculosis.
引用
收藏
页码：683 / 688
页数：6
相关论文
共 50 条
  • [21] Drug therapy of diffuse Dunndarmangiodysplasien with Octrotid and thalidomide
    Schachner, Andrea
    Amrein, Karin
    Schreiber, Florian
    Hoegenauer, Christoph
    WIENER KLINISCHE WOCHENSCHRIFT, 2009, 121 (15-16) : A25 - A25
  • [22] Thalidomide: From tragedy to new drug discovery
    Muller, GW
    CHEMTECH, 1997, 27 (01) : 21 - 25
  • [23] THALIDOMIDE INDUCED NEUROPATHY AND DRUG METABOLIC POLYMORPHISM
    HARLAND, CC
    STEVENTON, GB
    MARSDEN, JR
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1993, 100 (04) : 492 - 492
  • [24] Thalidomide in solid tumours: the resurrection of an old drug
    Sleijfer, S
    Kruit, WHJ
    Stoter, G
    EUROPEAN JOURNAL OF CANCER, 2004, 40 (16) : 2377 - 2382
  • [25] The rebirth of isolated organ contraction studies for drug discovery and repositioning
    Borges, Ricardo
    DRUG DISCOVERY TODAY, 2022, 27 (04) : 1128 - 1131
  • [26] Research rebirth - Companies seeking solutions to emerging drug resistance
    Hoffert, SP
    SCIENTIST, 1998, 12 (08): : 1 - +
  • [27] Thalidomide in dermatology. New indications for an old drug
    Calderon, P
    Anzilotti, M
    Phelps, R
    INTERNATIONAL JOURNAL OF DERMATOLOGY, 1997, 36 (12) : 881 - 887
  • [28] Thalidomide: a new old drug in the treatment of multiple myeloma
    Abdel-Razeq, HN
    Mousa, SA
    DRUGS OF THE FUTURE, 2004, 29 (10) : 1059 - 1063
  • [29] Thalidomide-A Notorious Sedative to a Wonder Anticancer Drug
    Zhou, Shuang
    Wang, Fengfei
    Hsieh, Tze-Chen
    Wu, Joseph M.
    Wu, Erxi
    CURRENT MEDICINAL CHEMISTRY, 2013, 20 (33) : 4102 - 4108
  • [30] THE 'REBIRTH OF NATURE' AND THE REBIRTH OF SHELLEY
    FREEMAN, J
    BYRON JOURNAL, 1994, (22): : 50 - 62
12345