Functional universality and evolutionary diversity: insights from the structure of the ribosome

被引:26
|
作者
Yonath, A [1 ]
Franceschi, F
机构
[1] Max Planck Unit Struct Mol Biol, D-22603 Hamburg, Germany
[2] Weizmann Inst Sci, Dept Biol Struct, IL-76100 Rehovot, Israel
[3] Max Planck Inst Mol Genet, D-14195 Berlin, Germany
来源
STRUCTURE WITH FOLDING & DESIGN | 1998年 / 6卷 / 06期
关键词
D O I
10.1016/S0969-2126(98)00069-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The structure of the mammalian ribosome, reconstructed at 25 Angstrom resolution, has added a new dimension to our current knowledge, as it manifests the conservation and universality of the ribosome in respect to its primary tasks in protein biosynthesis, A combined approach to study of the ribosome, using X-ray crystallography and electron microscopy, may further improve our understanding of ribosome function in the future.
引用
收藏
页码:679 / 684
页数:6
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