Intracerebral hemorrhage in mouse models: therapeutic interventions and functional recovery

被引：16
|
作者：
Kathirvelu, Balachandar [1 ]
Carmichael, S. Thomas [1 ]
机构：
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurol, Los Angeles, CA 90095 USA
来源：
METABOLIC BRAIN DISEASE | 2015年 / 30卷 / 02期
关键词：
ICH; Collagenase; Autologous blood; Functional recovery; MIDBRAIN DOPAMINERGIC-NEURONS; ACID RECEPTOR STIMULATION; RETINOIC ACID; PROLONGED HYPOTHERMIA; NEUROTROPHIC FACTOR; MICROGLIAL ACTIVATION; STROKE-COUNCIL; UP-REGULATION; BRAIN-INJURY; TNF-ALPHA;
D O I：
10.1007/s11011-014-9559-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
There has been strong pre-clinical research on mechanisms of initial cell death and tissue injury in intracerebral hemorrhage (ICH). This data has led to the evaluation of several therapeutics for neuroprotection or the mitigation of early tissue damage. Most of these studies have been done in the rat. Also, there has been little study of the mechanisms of tissue repair and recovery. This review examines the testing of candidate therapeutics in mouse models of ICH for their effect on tissue protection and repair. This review will help the readers compare it to the extensively researched rat model of ICH and thus enhance work that are pending in mouse model.
引用
收藏
页码：449 / 459
页数：11
相关论文
共 50 条
  • [1] Intracerebral hemorrhage in mouse models: therapeutic interventions and functional recovery
    Balachandar Kathirvelu
    S. Thomas Carmichael
    Metabolic Brain Disease, 2015, 30 : 449 - 459
  • [2] THERAPEUTIC INTERVENTIONS TO PREVENT INTRACEREBRAL HEMORRHAGE IN PRETERM INFANTS
    KAUFFMAN, RE
    JOURNAL OF PEDIATRICS, 1986, 108 (02): : 323 - 325
  • [3] Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery
    Li, Hongmin
    Ghorbani, Samira
    Oladosu, Olayinka
    Zhang, Ping
    Visser, Frank
    Dunn, Jeff
    Zhang, Yunyan
    Ling, Chang-Chun
    Yong, V. Wee
    Xue, Mengzhou
    JOURNAL OF NEUROINFLAMMATION, 2025, 22 (01)
  • [4] Therapeutic Effect of Nicotine in a Mouse Model of Intracerebral Hemorrhage
    Hijioka, Masanori
    Matsushita, Hideaki
    Hisatsune, Akinori
    Isohama, Yoichiro
    Katsuki, Hiroshi
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2011, 338 (03): : 741 - 749
  • [5] Therapeutic effect of allicin in a mouse model of intracerebral hemorrhage
    Atef, Yara
    Kinoshita, Keita
    Ichihara, Yusei
    Ushida, Keisuke
    Hirata, Yuma
    Kurauchi, Yuki
    Seki, Takahiro
    Katsuki, Hiroshi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2023, 153 (04) : 208 - 214
  • [6] Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage
    Xu, Jiake
    Duan, Zhongxin
    Qi, Xin
    Ou, Yi
    Guo, Xi
    Zi, Liu
    Wei, Yang
    Liu, Hao
    Ma, Lu
    Li, Hao
    You, Chao
    Tian, Meng
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 8
  • [7] Intracerebral Hemorrhage Deteriorates the Mortality and Slows Functional Recovery in a Mouse Model of Alzheimer's Disease.
    Hayashi, Kenyu
    Hasegawa, Yu
    Takemoto, Yushin
    Mukasa, Akitake
    Kim-Mitsuyama, Shokei
    STROKE, 2019, 50
  • [8] Emergent interventions for intracerebral hemorrhage
    Ross, KB
    JOURNAL OF MEDICAL SPEECH-LANGUAGE PATHOLOGY, 2005, 13 (04) : IX - XII
  • [9] Mouse intracerebral hemorrhage models produce different degrees of initial and delayed damage, axonal sprouting, and recovery
    Barratt, Harriet E.
    Lanman, Tyler A.
    Carmichael, S. Thomas
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2014, 34 (09): : 1463 - 1471
  • [10] INTRACEREBRAL HEMORRHAGE WITH RAPID RECOVERY
    SCOTT, WR
    MILLER, BR
    ARCHIVES OF NEUROLOGY, 1985, 42 (02) : 133 - 136
12345