Crystal structures of two polymorphs of tixocortol pivalate

被引：0

作者：

Rousselin, Yoann ^{[1
]}

Yolka, Sylvie ^{[2
]}

Clavel, Alexandre ^{[2
]}

机构：

[1] Univ Bourgogne Franche Comte, ICMUB UMR 6302, 9 Ave Alain Savary, F-21000 Dijon, France

[2] M2i Salin, 36 Route Arles RD 36, F-13129 Salin De Giraud, France

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2021年 / 77卷

关键词：

tixocortol; pivalone; crystal structure; polymorphs; CONTACT HYPERSENSITIVITY;

D O I：

10.1107/S2056989021007167

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

Two polymorphs, (I) and (II), of (S)-{2-[(8S,9S,10R,11S,13S,14S,17R)-11,17dihydroxy-10,13- dimethyl- 3- oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[ a]phenanthren-17-yl]-2-oxoethyl} 2,2- dimethylpropanethioate, C26H38O5S, have been identified. They are orthorhombic, non-centrosymmetric (P(2)1(2)1(2)1). The structures display layers of molecules conected via O-H center dot center dot center dot O hydrogen bonds along the b-axis direction in polymorph (I) and along the c-axis direction in polymorph (II). The structure of ( II) exhibits disorder of the main molecule.

引用

页码：809 / +

页数：20

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