Reagent-Controlled Lithiation-Borylation

被引：25
|
作者：
Leonori, Daniele [1 ]
Aggarwal, Varinder K. [1 ]
机构：
[1] Univ Bristol, Sch Chem, Bristol, Avon, England
来源：
SYNTHESIS AND APPLICATION OF ORGANOBORON COMPOUNDS | 2015年 / 49卷
基金：
英国工程与自然科学研究理事会;
关键词：
1,2-Metallate rearrangement; Boronic esters; Stereospecific; Homologation; Lithiated carbamates; Total synthesis; TERTIARY BORONIC ESTERS; STEREOCONTROLLED SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; STEREOSPECIFIC CONVERSION; SECONDARY ALCOHOLS; HOMOALDOL REACTION; HOMOLOGATION; METHODOLOGY; ALKYL;
D O I：
10.1007/978-3-319-13054-5_9
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
This chapter focuses on the stereo-controlled homologation of chiral boronic esters with chiral lithium carbenoid (lithiation-borylation) as a powerful method for the asymmetric synthesis of many complex molecules. It is highlighted that the potential methodology to create multiple contiguous stereogenic centers on "growing" carbon chains.
引用
收藏
页码：271 / 295
页数：25
相关论文
共 50 条
12345