Reagent-Controlled Lithiation-Borylation

被引：25

作者：

Leonori, Daniele ^{[1
]}

Aggarwal, Varinder K. ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Bristol, Avon, England

来源：

SYNTHESIS AND APPLICATION OF ORGANOBORON COMPOUNDS | 2015年 / 49卷

基金：

英国工程与自然科学研究理事会;

关键词：

1,2-Metallate rearrangement; Boronic esters; Stereospecific; Homologation; Lithiated carbamates; Total synthesis; TERTIARY BORONIC ESTERS; STEREOCONTROLLED SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; ASYMMETRIC-SYNTHESIS; STEREOSPECIFIC CONVERSION; SECONDARY ALCOHOLS; HOMOALDOL REACTION; HOMOLOGATION; METHODOLOGY; ALKYL;

D O I：

10.1007/978-3-319-13054-5_9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This chapter focuses on the stereo-controlled homologation of chiral boronic esters with chiral lithium carbenoid (lithiation-borylation) as a powerful method for the asymmetric synthesis of many complex molecules. It is highlighted that the potential methodology to create multiple contiguous stereogenic centers on "growing" carbon chains.

引用

页码：271 / 295

页数：25

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